SCHEMBL1282328

SCHEMBL1282328

CN(C)C(C)(CCC(N)=O)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.31
GGT1 P19440 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
THRB P10828 1/20 0.31
NAALAD2 Q9Y3Q0 1/20 0.31
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1282326 1.00 KMT2A (0.31) KMT2AGGT1MEN1ALDH1A1CYP1A2
SCHEMBL6064423 0.85
SCHEMBL23576186 0.83 NAALAD2 (0.45) KMT2AMEN1ALDH1A1CYP1A2THRB
SCHEMBL3180159 0.82 GGT1 (0.31) KMT2AGGT1MEN1ALDH1A1CYP1A2
SCHEMBL27752979 0.82 GGT1 (0.31) KMT2AGGT1MEN1ALDH1A1CYP1A2
SCHEMBL5716372 0.82 GGT1 (0.34) KMT2AGGT1MEN1ALDH1A1CYP1A2
SCHEMBL31026562 0.81 ALDH1A1 (0.38) ALDH1A1NAALAD2
SCHEMBL27396655 0.81 SOAT1 (0.46) KMT2AMEN1ALDH1A1CYP1A2ALOX15
Octadecanoic Acid Amide SCHEMBL28012042 0.81 SOAT1 (0.46) KMT2AMEN1ALDH1A1CYP1A2ALOX15
SCHEMBL1281745 0.78 TSHR (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118256591-A Cyclic peptide compound having high membrane permeability and library comprising same 中外制药株式会社 2024-06-28 CN disclosed
CN-110869544-B Cyclic peptide compound having high membrane permeability and library comprising same 中外制药株式会社 2024-03-08 CN disclosed
CN-110869544-A Cyclic peptide compound having high membrane permeability and library containing same 中外制药株式会社 2020-03-06 CN disclosed
US-9005920-B2 Solution for cell-free protein synthesis, kit for cell-free protein synthesis, and method of protein synthesis TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2015-04-14 US disclosed
EP-2447365-A1 CELL-FREE PROTEIN SYNTHESIS SOLUTION, CELL-FREE PROTEIN SYNTHESIS KIT, AND PROTEIN SYNTHESIS METHOD Toyota Jidosha Kabushiki Kaisha (JP) 2012-05-02 EP disclosed
US-20120088269-A1 SOLUTION FOR CELL-FREE PROTEIN SYNTHESIS, KIT FOR CELL-FREE PROTEIN SYNTHESIS, AND METHOD OF PROTEIN SYNTHESIS TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2012-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088269-A1 SOLUTION FOR CELL-FREE PROTEIN SYNTHESIS, KIT FOR CELL-FREE PROTEIN SYNTHESIS, AND METHOD OF PROTEIN SYNTHESIS SMS, RNMT, SET KMT2A 651/4885GGT1 722/4885MEN1 719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.