Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | OXTR | P30559 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.45 |
| ▸ | CBR1 | P16152 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12826226 | 0.87 | MEN1 (0.47) | LMNAOXTRHPGDMAPTHTT | |
| SCHEMBL12825956 | 0.82 | ALDH1A1 (0.47) | LMNAOXTRHPGDSLC6A2SLC6A3 | |
| SCHEMBL12825465 | 0.78 | P2RX3 (0.50) | LMNAHTTALDH1A1ATML3MBTL1 | |
| SCHEMBL5402614 | 0.78 | HSP90B1 (0.43) | LMNATTRHPGDSLC6A2SLC6A3 | |
| SCHEMBL12825881 | 0.76 | ALDH1A1 (0.42) | LMNATTROXTRHPGDSLC6A2 | |
| SCHEMBL28148104 | 0.75 | LMNA (0.46) | LMNATTRHPGDSLC6A2SLC6A3 | |
| SCHEMBL7674060 | 0.74 | S1PR4 (0.50) | LMNATTROXTRHPGDSLC6A2 | |
| SCHEMBL12825410 | 0.74 | EGFR (0.53) | LMNASLC6A2SLC6A3HTTALDH1A1 | |
| SCHEMBL12825478 | 0.73 | KMT2A (0.48) | LMNAHPGDMAPTHTTALDH1A1 | |
| SCHEMBL12825415 | 0.73 | MAPT (0.40) | MAPTALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1533303-B1 | Substituted Aminosalicylacid Amides ( intermediates ) | BAYER CROPSCIENCE AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| EP-2292608-A1 | Intermediates for the preparation of substituted Aminosalicylic acid amides with fungicidal activity | Bayer CropScience AG (DE) | 2011-03-09 | — | — | EP | disclosed |