Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 3/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12745665 | 0.83 | PRKCA (0.35) | PRKCAALOX12AKT1SORT1 | |
| SCHEMBL12745666 | 0.83 | PRKCA (0.35) | PRKCAALOX12AKT1SORT1 | |
| SCHEMBL1463809 | 0.83 | PRKCA (0.35) | PRKCAALOX12AKT1SORT1 | |
| SCHEMBL12746067 | 0.74 | PRKCA (0.37) | PRKCAAKT1 | |
| SCHEMBL12745986 | 0.69 | DDB1 (0.41) | — | |
| SCHEMBL1463688 | 0.66 | SIRT2 (0.32) | — | |
| SCHEMBL12074023 | 0.58 | ALDH1A1 (0.33) | — | |
| SCHEMBL28541009 | 0.58 | PIK3CD (0.33) | PRKCAALOX12AKT1 | |
| SCHEMBL11692507 | 0.56 | PRKCA (0.38) | PRKCA | |
| SCHEMBL17960486 | 0.56 | LMNA (0.34) | PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071097-A1 | CEPHALOTAXUS ESTERS, METHODS OF SYNTHESIS, AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071097-A1 | CEPHALOTAXUS ESTERS, METHODS OF SYNTHESIS, AND USES THEREOF | COASY, CXCR4, CETP | PRKCA 2723/4885ALOX12 13/4885AKT1 1629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.