SCHEMBL12827076

SCHEMBL12827076

CCCCN(CCCC)C(=O)CC(=O)OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 4/20 0.47
▸ CA9 Q16790 3/20 0.47
▸ CA1 P00915 2/20 0.47
▸ MMP1 P03956 1/20 0.44
▸ MMP2 P08253 1/20 0.44
▸ MMP3 P08254 1/20 0.44
▸ MMP8 P22894 1/20 0.44
▸ KDM5A P29375 4/20 0.42
▸ POLB P06746 1/20 0.42
▸ POLA1 P09884 1/20 0.42
▸ SIGMAR1 Q99720 1/20 0.40
▸ CYP1A2 P05177 1/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ TSHR P16473 2/20 0.39
▸ MGAM O43451 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ SI P14410 1/20 0.39
▸ MGAM2 Q2M2H8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283713 0.84 CA12 (0.56) CA12CA9CA1MMP1MMP2
SCHEMBL1129612 0.78 CA12 (0.50) CA12CA9CA1MMP1MMP2
SCHEMBL2417403 0.78 CA12 (0.50) CA12CA9CA1MMP1MMP2
SCHEMBL3625206 0.78 CA12 (0.48) CA12CA9CA1MMP1MMP2
SCHEMBL10369219 0.77 GAA (0.48) CA12CA9CA1MMP1MMP2
SCHEMBL16922397 0.77 KDM5A (0.55) CA12CA9CA1KDM5APOLB
SCHEMBL15016405 0.77 CA12 (0.48) CA12CA9CA1MMP1MMP2
SCHEMBL10339549 0.77 ALDH1A1 (0.52) CA12CA9CA1MMP1MMP2
SCHEMBL30364158 0.77 CA12 (0.48) CA12CA9CA1MMP1MMP2
SCHEMBL15520237 0.77 CA12 (0.48) CA12CA9CA1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10113052-B2 5H-furan-2-one derivatives stabilization of organic material BASF SE (DE) 2018-10-30 — — US disclosed
US-20160362535-A1 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL BASF SCHWEIZ AG (CH) 2016-12-15 — — US disclosed
US-20160362535-A1 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL BASF SCHWEIZ AG (CH) 2016-12-15 — — US disclosed
US-20160362535-A1 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL BASF SCHWEIZ AG (CH) 2016-12-15 — — US disclosed
US-9458380-B2 5H-furan-2-one derivatives for stabilization of organic material BASF SE (DE) 2016-10-04 — — US disclosed
US-9458380-B2 5H-furan-2-one derivatives for stabilization of organic material BASF SE (DE) 2016-10-04 — — US disclosed
US-9458380-B2 5H-furan-2-one derivatives for stabilization of organic material BASF SE (DE) 2016-10-04 — — US disclosed
EP-2705082-B1 5H-FURAN-2-ONE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIAL BASF SE (DE) 2015-09-23 — — EP disclosed
EP-2705082-A1 5H-FURAN-2-ONE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIAL BASF SE (DE) 2014-03-12 — — EP disclosed
US-20140058021-A1 5H-Furan-2-one Derivatives for Stabilization of Organic Material BASF SE (DE) 2014-02-27 — — US disclosed
US-20140058021-A1 5H-Furan-2-one Derivatives for Stabilization of Organic Material BASF SE (DE) 2014-02-27 — — US disclosed
US-20140058021-A1 5H-Furan-2-one Derivatives for Stabilization of Organic Material BASF SE (DE) 2014-02-27 — — US disclosed
WO-2012150527-A1 5H-FURAN-2-ONE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIAL BASF SE (DE) 2012-11-08 — — WO disclosed
WO-2012150527-A1 5H-FURAN-2-ONE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIAL BASF SE (DE) 2012-11-08 — — WO disclosed
US-20110070657-A1 DETECTING IONS AND MEASURING ION CONCENTRATIONS THE GENERAL HOSPITAL CORPORATION (US) 2011-03-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110070657-A1 DETECTING IONS AND MEASURING ION CONCENTRATIONS CA2, SLC30A5, CA3 CA12 68/4885CA9 188/4885CA1 36/4885
US-10113052-B2 5H-furan-2-one derivatives stabilization of organic material C5, C9, CBR1 CA12 3633/4885CA9 3636/4885CA1 3060/4885
US-20160362535-A1 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL C5, C9, CBR1 CA12 3633/4885CA9 3636/4885CA1 3060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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