Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.38 |
| ▸ | DCPS | Q96C86 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475655 | 0.85 | ACHE (0.42) | ACHE | |
| SCHEMBL1474786 | 0.85 | PKM (0.45) | ACHEDCPS | |
| SCHEMBL1475041 | 0.85 | DCPS (0.44) | DCPS | |
| SCHEMBL1475382 | 0.85 | MAPT (0.45) | DCPS | |
| SCHEMBL1475267 | 0.85 | DCPS (0.44) | DCPSCYP2D6 | |
| SCHEMBL12748688 | 0.85 | ACHE (0.39) | ACHEDCPSGSK3B | |
| SCHEMBL1476053 | 0.84 | MEN1 (0.43) | DCPS | |
| SCHEMBL1475638 | 0.83 | ACHE (0.37) | ACHEDCPS | |
| SCHEMBL1476245 | 0.83 | RBP4 (0.47) | ACHEDCPS | |
| SCHEMBL1477099 | 0.83 | DCPS (0.47) | DCPSCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915274-B2 | Nitrogen containing heterocyclic compounds and medicines containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-03-29 | — | — | US | disclosed |