Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KRAS | P01116 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CPS1 | P31327 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27581775 | 0.82 | MEP1B (0.43) | MEP1BCES2CES1TUBB1HIF1A | |
| SCHEMBL5743863 | 0.81 | HPGDS (0.46) | MEP1BCES2CES1TUBB1SMN1; SMN2 | |
| SCHEMBL27878806 | 0.77 | MEP1B (0.43) | MEP1BCES2CES1TUBB1SMN1; SMN2 | |
| SCHEMBL27778992 | 0.77 | MEP1B (0.40) | MEP1BCES2CES1TUBB1SMN1; SMN2 | |
| SCHEMBL116280 | 0.76 | CES2 (0.45) | MEP1BCES2CES1TUBB1LMNA | |
| SCHEMBL606872 | 0.76 | TDP1 (0.49) | MEP1BCES2CES1TUBB1LMNA | |
| SCHEMBL24918 | 0.75 | CES2 (0.44) | MEP1BCES2CES1TUBB1HIF1A | |
| SCHEMBL201535 | 0.75 | CES2 (0.44) | MEP1BCES2CES1TUBB1LMNA | |
| SCHEMBL3808483 | 0.75 | CES2 (0.48) | MEP1BCES2CES1SMN1; SMN2LMNA | |
| SCHEMBL116517 | 0.75 | MEN1 (0.50) | MEP1BCES2CES1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915418-B2 | Intermediates and process for the production of optically active quinolonecarboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2011-03-29 | — | — | US | disclosed |
| US-7626029-B2 | Into a difluorobenzoic acid, for producting quinolonecarboxylic acid serving as synthetic antibacterial agent, medicament, agricultural chemical, or veterinary drug; ionic liquid solvents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-12-01 | — | — | US | disclosed |