Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12798968 | 0.85 | MEN1 (0.43) | MEN1KMT2ANPC1HTT | |
| SCHEMBL14818553 | 0.79 | IL2 (0.35) | MEN1KMT2ANPC1 | |
| SCHEMBL12830018 | 0.79 | LMNA (0.48) | MEN1KMT2ANPC1HTT | |
| SCHEMBL12830419 | 0.77 | CASP3 (0.38) | MEN1KMT2ANPC1NTRK1 | |
| SCHEMBL12830118 | 0.75 | RAB9A (0.53) | MEN1KMT2ANPC1 | |
| SCHEMBL12756865 | 0.74 | POLB (0.49) | MEN1KMT2ANPC1HTTNTRK1 | |
| SCHEMBL12756620 | 0.74 | NTRK1 (0.36) | MEN1KMT2ANPC1HTTKDM4C | |
| SCHEMBL12831283 | 0.74 | ALOX15 (0.37) | MEN1KMT2ANPC1HTTKDM4C | |
| SCHEMBL12830144 | 0.73 | RAB9A (0.50) | NPC1NTRK1 | |
| SCHEMBL12756866 | 0.73 | MEN1 (0.44) | MEN1KMT2ANPC1HTTKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034962-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-03-24 | — | — | WO | disclosed |