Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4940818 | 0.86 | L3MBTL1 (0.62) | L3MBTL1TDP1CTBP2KMT2AMEN1 | |
| SCHEMBL12731519 | 0.83 | L3MBTL1 (0.61) | L3MBTL1TDP1GSK3BCTBP2KMT2A | |
| SCHEMBL18371865 | 0.81 | MEN1 (0.64) | L3MBTL1TDP1CTBP2KMT2AMEN1 | |
| SCHEMBL7148258 | 0.80 | L3MBTL1 (0.56) | L3MBTL1TDP1CTBP2KMT2AMEN1 | |
| SCHEMBL5042101 | 0.80 | GSK3B (0.50) | L3MBTL1GSK3BKMT2AMEN1RAB9A | |
| SCHEMBL6238483 | 0.80 | CA2 (0.58) | CTBP2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL10247190 | 0.79 | L3MBTL1 (0.61) | L3MBTL1TDP1GSK3BRAB9ANPC1 | |
| SCHEMBL559059 | 0.78 | TPMT (0.38) | GSK3B | |
| SCHEMBL756910 | 0.78 | PTPN1 (0.52) | TDP1CTBP2KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL14149286 | 0.78 | CPA1 (0.38) | L3MBTL1TDP1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9144573-B2 | Prostaglandin transporter inhibitors | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2015-09-29 | — | — | US | disclosed |
| US-20130171171-A1 | PROSTAGLANDIN TRANSPORTER INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2013-07-04 | — | — | US | disclosed |
| US-20130030001-A1 | QUINUCLIDINE DERIVATIVES AS MUSCARINIC M3 RECEPTOR ANTAGONISTS | PULMAGEN THERAPEUTICS (SYNERGY) LIMITED (GB) | 2013-01-31 | — | — | US | disclosed |
| US-8329729-B2 | Quinuclidine derivatives as muscarinic M3 receptor antagonists | ASTRAZENECA AB (SE) | 2012-12-11 | — | — | US | disclosed |
| US-20110172237-A1 | QUINUCLIDINE DERIVATIVES AS MUSCARINIC M3 RECEPTOR ANTAGONISTS | ASTRAZENECA UK LIMITED (GB) | 2011-07-14 | — | — | US | disclosed |
| WO-2011038293-A1 | CYCLIC PEPTIDE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130171171-A1 | PROSTAGLANDIN TRANSPORTER INHIBITORS | SLC47A2, PTGES2, PTGS2 | L3MBTL1 4532/4885TDP1 3107/4885GSK3B 3759/4885 |
| US-20110172237-A1 | QUINUCLIDINE DERIVATIVES AS MUSCARINIC M3 RECEPTOR ANTAGONISTS | CHRM3, CHRM2, CHRM1 | L3MBTL1 3522/4885TDP1 4196/4885GSK3B 1466/4885 |
| US-20130030001-A1 | QUINUCLIDINE DERIVATIVES AS MUSCARINIC M3 RECEPTOR ANTAGONISTS | CHRM3, CHRM2, CHRM5 | L3MBTL1 4214/4885TDP1 3997/4885GSK3B 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.