Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13432984 | 0.81 | MEN1 (0.44) | L3MBTL1LMNAGAAHTT | |
| SCHEMBL5042101 | 0.80 | GSK3B (0.50) | L3MBTL1LMNAGAAHTT | |
| SCHEMBL6238483 | 0.80 | CA2 (0.58) | CA2CAMK2ALMNAGAAFNTA | |
| SCHEMBL559059 | 0.78 | TPMT (0.38) | CA2CAMK2A | |
| SCHEMBL622333 | 0.78 | GSK3B (0.52) | TDP1L3MBTL1LMNAHTT | |
| SCHEMBL12831753 | 0.78 | L3MBTL1 (0.55) | TDP1L3MBTL1LMNAGAA | |
| SCHEMBL756910 | 0.78 | PTPN1 (0.52) | TDP1LMNAGAAHTT | |
| SCHEMBL1892394 | 0.77 | CES1 (0.58) | CPA1TDP1L3MBTL1CES2CES1 | |
| SCHEMBL4954745 | 0.77 | ALDH1A1 (0.52) | CA2TDP1L3MBTL1CES2CES1 | |
| SCHEMBL12831751 | 0.75 | LMNA (0.64) | ABCC4LMNAGAATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660465-B1 | PROCESS FOR THE SYNTHESIS OF BIARYL OXAZOLIDINONES | MELINTA THERAPEUTICS INC (US) | 2014-12-17 | — | — | EP | disclosed |
| US-8324398-B2 | Process for the synthesis of biaryl oxazolidinones | RIB-X PHARMACEUTICALS, INC. (US) | 2012-12-04 | — | — | US | disclosed |