Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.45 |
| ▸ | CCR6 | P51684 | 3/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12822356 | 0.87 | IDH1 (0.44) | TBXAS1CHRM5MAPTKMT2AHSP90AA1 | |
| SCHEMBL29906466 | 0.87 | IDH1 (0.44) | TBXAS1CHRM5MAPTKMT2AHSP90AA1 | |
| SCHEMBL12833649 | 0.86 | TBXAS1 (0.55) | TBXAS1MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL29906394 | 0.86 | MAOA (0.50) | TBXAS1CHRM5MAPTALDH1A1LMNA | |
| SCHEMBL12760719 | 0.86 | MAOA (0.50) | TBXAS1CHRM5MAPTALDH1A1LMNA | |
| SCHEMBL12822344 | 0.86 | MAOA (0.50) | TBXAS1CHRM5MAPTALDH1A1LMNA | |
| SCHEMBL29906407 | 0.86 | HIF1A (0.50) | CHRM5MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL26982495 | 0.86 | HIF1A (0.50) | CHRM5MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL29906366 | 0.85 | CHRM5 (0.46) | CHRM5MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL26982494 | 0.85 | CHRM5 (0.46) | CHRM5MAPTALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118439940-A | Preparation method and application of 1, 4-naphthoquinone compound | 珠海科技学院 | 2024-08-06 | — | — | CN | disclosed |
| EP-2257515-B1 | 1,4-NAPHTHOQUINONE DERIVATIVES AND THERAPEUTIC USE THEREOF | CENTRE NAT RECH SCIENT (FR) | 2017-05-17 | — | — | EP | disclosed |
| US-9090549-B2 | 1,4-naphthoquinones derivatives and therapeutic use thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2015-07-28 | — | — | US | disclosed |
| US-20110059972-A1 | 1,4-NAPHTHOQUINONES DERIVATIVES AND THERAPEUTIC USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059972-A1 | 1,4-NAPHTHOQUINONES DERIVATIVES AND THERAPEUTIC USE THEREOF | NQO1, NDUFV2, RECQL | TBXAS1 183/4885CHRM5 4784/4885MAPT 2505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.