Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 11/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 5/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19480442 | 0.80 | DDAH1 (0.56) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| Trifluoroacetic Acid SCHEMBL20945171 | 0.78 | DDAH1 (0.54) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| SCHEMBL14479038 | 0.78 | DDAH1 (0.58) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| SCHEMBL19480556 | 0.75 | DDAH1 (0.47) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| SCHEMBL10968265 | 0.75 | DDAH1 (0.63) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| SCHEMBL22116931 | 0.75 | SRD5A2 (0.48) | TDP1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL3339259 | 0.74 | DDAH1 (0.61) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| SCHEMBL14000501 | 0.74 | DDAH1 (0.61) | DDAH1MGLLHSP90AA1NPSR1TDP1 | |
| SCHEMBL22116994 | 0.74 | POLB (0.61) | HSP90AA1TDP1ALDH1A1HTTMEN1 | |
| SCHEMBL29555730 | 0.74 | GAA (0.70) | TDP1ALDH1A1HTTMEN1CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298736-B1 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | SOLULINK INC (US) | 2015-07-15 | — | — | EP | disclosed |
| EP-2298736-A1 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | Solulink, Inc. (US) | 2011-03-23 | — | — | EP | disclosed |
| EP-2295407-A1 | Hydrazine-based and carbonyl-based bifunctional crosslinking reagents | Solulink, Inc. (US) | 2011-03-16 | — | — | EP | disclosed |