Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.54 |
| ▸ | AOC2 | O75106 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 7/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3339259 | 0.89 | DDAH1 (0.61) | DDAH1AOC2HSP90AA1ALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL17969213 | 0.88 | DDAH1 (0.59) | DDAH1AOC2HSP90AA1ALDH1A1NPSR1 | |
| SCHEMBL12834399 | 0.78 | DDAH1 (0.51) | DDAH1HSP90AA1ALDH1A1NPSR1TDP1 | |
| Trifluoroacetic Acid SCHEMBL27664698 | 0.76 | PLOD2 (0.53) | ALDH1A1KDM4EMPOCYP3A4KDM5A | |
| Benzoic Acid Hydrazide SCHEMBL5591378 | 0.76 | CES1 (0.52) | AOC2ALDH1A1KDM4EMPOCYP3A4 | |
| Trifluoroacetic Acid SCHEMBL18261423 | 0.75 | HSP90AA1 (0.43) | DDAH1HSP90AA1ALDH1A1NPSR1TDP1 | |
| SCHEMBL10968265 | 0.74 | DDAH1 (0.63) | DDAH1HSP90AA1ALDH1A1NPSR1TDP1 | |
| SCHEMBL28901118 | 0.74 | DDAH1 (0.59) | DDAH1HSP90AA1ALDH1A1NPSR1TDP1 | |
| SCHEMBL17235983 | 0.73 | CYP1A2 (0.57) | DDAH1HSP90AA1ALDH1A1NPSR1TDP1 | |
| SCHEMBL14000501 | 0.73 | DDAH1 (0.61) | DDAH1HSP90AA1ALDH1A1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002222-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | 3R VALO, S.E.C. (CA) | 2021-01-07 | — | — | US | disclosed |
| EP-3442943-B1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | 3R VALO S E C (CA) | 2020-10-07 | — | — | EP | disclosed |
| US-10759754-B2 | Aminobenzoic acid derivatives for use as anti-inflammatory agents, anti-metastatic agents and/or anticancer agents | 3R VALO, S.E.C. (CA) | 2020-09-01 | — | — | US | disclosed |
| US-20190127325-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | UNIVERSITÉ DU QUÉBEC À TROIS-RIVIÈRES (CA) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002222-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | NFKBIA, NFKB1, NFRKB | DDAH1 1457/4885AOC2 2224/4885HSP90AA1 510/4885 |
| US-20190127325-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | NFKBIA, NFKB1, NFRKB | DDAH1 1457/4885AOC2 2224/4885HSP90AA1 510/4885 |
| US-10759754-B2 | Aminobenzoic acid derivatives for use as anti-inflammatory agents, anti-metastatic agents and/or anticancer agents | NFKBIA, NFKB1, NFRKB | DDAH1 1457/4885AOC2 2224/4885HSP90AA1 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.