Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 6/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19480554 | 0.85 | CA12 (0.49) | ALDH1A1NPSR1HPGDHTTKMT2A | |
| SCHEMBL20945305 | 0.80 | ALDH1A1 (0.47) | TDP1ALDH1A1HSP90AA1NPSR1HPGD | |
| SCHEMBL20945003 | 0.80 | HSP90AA1 (0.56) | TDP1ALDH1A1HSP90AA1NPSR1HPGD | |
| SCHEMBL29032101 | 0.79 | HSP90AA1 (0.62) | DDAH1TDP1ALDH1A1HSP90AA1NPSR1 | |
| SCHEMBL19480442 | 0.79 | DDAH1 (0.56) | DDAH1TDP1ALDH1A1HSP90AA1NPSR1 | |
| SCHEMBL1477613 | 0.79 | MIF (0.50) | TDP1ALDH1A1KMT2AMAPTPOLB | |
| SCHEMBL25320235 | 0.78 | HDAC6 (0.55) | ALDH1A1NPSR1HPGDHTTPKM | |
| SCHEMBL14479038 | 0.77 | DDAH1 (0.58) | DDAH1TDP1ALDH1A1HSP90AA1NPSR1 | |
| SCHEMBL13605085 | 0.77 | MAPT (0.63) | TDP1ALDH1A1HPGDHTTKMT2A | |
| SCHEMBL17172491 | 0.77 | ALDH1A1 (0.66) | TDP1ALDH1A1HTTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002222-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | 3R VALO, S.E.C. (CA) | 2021-01-07 | — | — | US | disclosed |
| US-20210002222-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | 3R VALO, S.E.C. (CA) | 2021-01-07 | — | — | US | disclosed |
| EP-3442943-B1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | 3R VALO S E C (CA) | 2020-10-07 | — | — | EP | disclosed |
| US-10759754-B2 | Aminobenzoic acid derivatives for use as anti-inflammatory agents, anti-metastatic agents and/or anticancer agents | 3R VALO, S.E.C. (CA) | 2020-09-01 | — | — | US | disclosed |
| US-10759754-B2 | Aminobenzoic acid derivatives for use as anti-inflammatory agents, anti-metastatic agents and/or anticancer agents | 3R VALO, S.E.C. (CA) | 2020-09-01 | — | — | US | disclosed |
| US-20190127325-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | UNIVERSITÉ DU QUÉBEC À TROIS-RIVIÈRES (CA) | 2019-05-02 | — | — | US | disclosed |
| US-20190127325-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | UNIVERSITÉ DU QUÉBEC À TROIS-RIVIÈRES (CA) | 2019-05-02 | — | — | US | disclosed |
| WO-2017177316-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | 3R VALO, S.E.C. (CA) | 2017-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002222-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | NFKBIA, NFKB1, NFRKB | DDAH1 1457/4885TDP1 3339/4885ALDH1A1 324/4885 |
| US-20190127325-A1 | AMINOBENZOIC ACID DERIVATIVES FOR USE AS ANTI-INFLAMMATORY AGENTS, ANTI-METASTATIC AGENTS AND/OR ANTICANCER AGENTS | NFKBIA, NFKB1, NFRKB | DDAH1 1457/4885TDP1 3339/4885ALDH1A1 324/4885 |
| US-10759754-B2 | Aminobenzoic acid derivatives for use as anti-inflammatory agents, anti-metastatic agents and/or anticancer agents | NFKBIA, NFKB1, NFRKB | DDAH1 1457/4885TDP1 3339/4885ALDH1A1 324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.