SCHEMBL12834980

SCHEMBL12834980

CCC(O)CCC(N)C(C)=O

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SLC1A3 P43003 3/20 0.34
▸ SLC1A2 P43004 3/20 0.34
▸ SLC1A1 P43005 3/20 0.34
▸ NOS2 P35228 6/20 0.34
▸ NOS3 P29474 4/20 0.34
▸ NOS1 P29475 4/20 0.34
▸ GRIK1 P39086 1/20 0.32
▸ GRIK2 Q13002 1/20 0.32
▸ GCLC P48506 2/20 0.32
▸ CA1 P00915 1/20 0.30
▸ CA2 P00918 1/20 0.30
▸ DPP4 P27487 1/20 0.30
▸ DPP8 Q6V1X1 1/20 0.30
▸ DPP9 Q86TI2 1/20 0.30
▸ DPP7 Q9UHL4 1/20 0.30
▸ LAP3 P28838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15384688 0.82 SLC1A3 (0.48) SLC1A3SLC1A2SLC1A1NOS2NOS3
SCHEMBL24213302 0.78 NOS2 (0.33) SLC1A3SLC1A2SLC1A1NOS2NOS3
SCHEMBL22387071 0.78 NOS2 (0.33) SLC1A3SLC1A2SLC1A1NOS2NOS3
SCHEMBL20099156 0.77 BHMT (0.41) SLC1A3SLC1A2SLC1A1NOS2NOS3
SCHEMBL24125927 0.76 ALDH1A1 (0.37) SLC1A3SLC1A2SLC1A1NOS2NOS3
SCHEMBL6367974 0.75 — —
SCHEMBL14886193 0.75 — —
SCHEMBL8299449 0.75 — —
SCHEMBL2632763 0.75 — —
SCHEMBL5928059 0.75 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7897721-B2 Cyclic peptide compositions for treatment of sexual dysfunction PALATIN TECHNOLOGIES, INC. (US) 2011-03-01 — — US disclosed
US-20100121027-A1 Cyclic Peptide Compositions for Treatment of Sexual Dysfunction PALATIN TECHNOLOGIES, INC. (US) 2010-05-13 — — US disclosed
US-7473760-B2 Cyclic peptide compositions for treatment of sexual dysfunction PALATIN TECHNOLOGIES, INC. (US) 2009-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100121027-A1 Cyclic Peptide Compositions for Treatment of Sexual Dysfunction VIP, GNRHR, NPR1 SLC1A3 1046/4885SLC1A2 1932/4885SLC1A1 1395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback