7,8-Dihydroxyflavone

7,8-Dihydroxyflavone

SCHEMBL419316

O=c1cc(-c2ccccc2)oc2c(O)c(O)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 10/20 1.00
MAPT P10636 7/20 1.00
HPGD P15428 6/20 1.00
KDM4E B2RXH2 6/20 1.00
CYP19A1 P11511 6/20 1.00
ALDH1A1 P00352 5/20 1.00
CYP3A4 P08684 5/20 1.00
HSD17B10 Q99714 5/20 1.00
ALOX15 P16050 4/20 1.00
TP53 P04637 4/20 1.00
MAPK1 P28482 3/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
MAOA P21397 2/20 1.00
MAOB P27338 2/20 1.00
IKBKB O14920 1/20 1.00
NTRK2 Q16620 1/20 1.00
CYP2C9 P11712 4/20 0.76
CYP2C19 P33261 4/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
7,8-Dihydroxyflavone SCHEMBL29374601 1.00 TERT (1.00) TERTMAPTHPGDKDM4ECYP19A1
7,8-Dihydroxyflavone SCHEMBL21852713 0.98 TERT (0.97) TERTMAPTHPGDKDM4ECYP19A1
7,8-Dihydroxyflavone SCHEMBL29577498 0.94 TERT (0.89) TERTMAPTHPGDKDM4ECYP19A1
SCHEMBL31322174 0.88 TERT (1.00) TERTMAPTHPGDKDM4ECYP19A1
SCHEMBL4649959 0.88 TERT (1.00) TERTMAPTHPGDKDM4ECYP19A1
SCHEMBL4649946 0.87 TERT (1.00) TERTMAPTHPGDKDM4ECYP19A1
SCHEMBL6804531 0.86 TERT (0.81) TERTMAPTHPGDKDM4ECYP19A1
SCHEMBL6615955 0.85 TERT (0.74) TERTMAPTHPGDKDM4ECYP19A1
SCHEMBL31632435 0.85 CYP19A1 (0.74) TERTMAPTHPGDKDM4ECYP19A1
SCHEMBL31632309 0.85 CYP19A1 (0.74) TERTMAPTHPGDKDM4ECYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121197046-B External ear drops for promoting growth of auditory nerve and preparation method thereof 顾虹 2026-05-19 CN claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
EP-3346842-B1 STABLE INOCULANT COMPOSITIONS AND METHODS FOR PRODUCING SAME NOVONESIS PLANT BIOSOLUTIONS AS (DK) 2026-03-25 EP claimed
US-12502433-B2 Phosphonate-drug conjugates MASSACHUSETTS EYE AND EAR INFIRMARY (US) 2025-12-23 US claimed
US-20250346643-A1 TROPOMYOSIN KINASE RECEPTOR (TRK) LIGANDS AS THERAPEUTICS TO SUPPORT LIVER REGENERATION UNIV VANDERBILT (US) 2025-11-13 US claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
CN-119157821-B Double-crosslinked hydrogel and preparation method and application thereof 南方医科大学珠江医院 2025-06-17 CN claimed
EP-4558622-A1 METHODS AND COMPOSITIONS FOR GENERATING HUMAN MIDBRAIN DOPAMINERGIC NEURONS FROM NEURAL PROGENITOR CELLS Trailhead Biosystems Inc. (US) 2025-05-28 EP claimed
WO-2007057091-A1 FLAVONE SULFATES AND THEIR USE AS ANTIOXIDANTS MERCK PATENT GMBH (DE) 2007-05-24 WO claimed
WO-2007047579-A2 A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2007-04-26 WO claimed
US-20070048639-A1 Undercoat layer containing charge transfer molecule, andTiO2; imaging layer; charge transfer molecule complexes with the TiO2 to form coordination bonds and the coordination bonds provide a reduction in ghosting; electrophotographic imaging members; improved image quality XEROX CORPORATION (US) 2007-03-01 US claimed
US-20060229262-A1 Pharmaceutical composition for treatment of infection with drug resistant bacterium and disinfectant TOMIHIKO HIGUCHI (JP) 2006-10-12 US claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
US-20040229825-A1 Pharmaceutical composition for treatment of infection with drug resistant bacterium and disinfectant ALPS PHARMACEUTICAL IND., CO., LTD. (JP) 2004-11-18 US claimed
JP-2003504327-A 2003-02-04 JP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 EP claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO claimed
WO-1996031206-A2 FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS WARNER-LAMBERT COMPANY (US) 1996-10-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346643-A1 TROPOMYOSIN KINASE RECEPTOR (TRK) LIGANDS AS THERAPEUTICS TO SUPPORT LIVER REGENERATION HGF, HDGF, NTRK2 TERT 879/4885MAPT 3351/4885HPGD 1906/4885
US-12502433-B2 Phosphonate-drug conjugates MYOC, PTAFR, MTMR1 TERT 4095/4885MAPT 1325/4885HPGD 1954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.