Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 10/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | MAOA | P21397 | 2/20 | 1.00 |
| ▸ | MAOB | P27338 | 2/20 | 1.00 |
| ▸ | IKBKB | O14920 | 1/20 | 1.00 |
| ▸ | NTRK2 | Q16620 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 7,8-Dihydroxyflavone SCHEMBL419316 | 1.00 | TERT (1.00) | TERTMAPTHPGDKDM4ECYP19A1 | |
| 7,8-Dihydroxyflavone SCHEMBL21852713 | 0.98 | TERT (0.97) | TERTMAPTHPGDKDM4ECYP19A1 | |
| 7,8-Dihydroxyflavone SCHEMBL29577498 | 0.94 | TERT (0.89) | TERTMAPTHPGDKDM4ECYP19A1 | |
| SCHEMBL4649959 | 0.88 | TERT (1.00) | TERTMAPTHPGDKDM4ECYP19A1 | |
| SCHEMBL31322174 | 0.88 | TERT (1.00) | TERTMAPTHPGDKDM4ECYP19A1 | |
| SCHEMBL4649946 | 0.87 | TERT (1.00) | TERTMAPTHPGDKDM4ECYP19A1 | |
| SCHEMBL6804531 | 0.86 | TERT (0.81) | TERTMAPTHPGDKDM4ECYP19A1 | |
| SCHEMBL6615955 | 0.85 | TERT (0.74) | TERTMAPTHPGDKDM4ECYP19A1 | |
| SCHEMBL31632309 | 0.85 | CYP19A1 (0.74) | TERTMAPTHPGDKDM4ECYP19A1 | |
| SCHEMBL6618127 | 0.85 | TERT (0.78) | TERTMAPTHPGDKDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118440896-A | Method for protecting RGC-5 high sugar model by 7, 8-DHF | 上海市松江区中心医院（上海交通大学附属第一人民医院松江分院） | 2024-08-06 | — | — | CN | claimed |
| CN-116981450-A | Combination of antidepressants and dextromethorphan for the treatment of neuropsychiatric disorders | 安泰赛普生物风投二代有限责任公司 | 2023-10-31 | — | — | CN | claimed |
| US-20230332103-A1 | Methods and Compositions for Generating Human Forebrain Neural Progenitor Cells and for Maturation Thereof to Parvalbumin+ Interneurons | TRAILHEAD BIOSYSTEMS INC. | 2023-10-19 | — | — | US | claimed |
| CN-117821305-B | Bifidobacterium bifidum capable of remarkably improving host BDNF expression quantity and application thereof | 江南大学 | 2026-02-27 | — | — | CN | disclosed |
| CN-119157821-B | Double-crosslinked hydrogel and preparation method and application thereof | 南方医科大学珠江医院 | 2025-06-17 | — | — | CN | disclosed |
| CN-119326751-A | Application of 7, 8-dihydroxyflavone in preparation of medicines for preventing and treating pulmonary fibrosis | 江苏省苏北人民医院 | 2025-01-21 | — | — | CN | disclosed |
| CN-119157821-A | Double-crosslinked hydrogel and preparation method and application thereof | 南方医科大学珠江医院 | 2024-12-20 | — | — | CN | disclosed |
| CN-119112903-A | Nanometer preparation for regulating mechanical microenvironment of idiopathic pulmonary fibrosis and preparation method and application thereof | 中国药科大学 | 2024-12-13 | — | — | CN | disclosed |
| CN-119082283-A | Novel marker for autism and application thereof | 中南大学湘雅二医院 | 2024-12-06 | — | — | CN | disclosed |
| CN-118440896-A | Method for protecting RGC-5 high sugar model by 7, 8-DHF | 上海市松江区中心医院（上海交通大学附属第一人民医院松江分院） | 2024-08-06 | — | — | CN | disclosed |
| CN-118440896-A | Method for protecting RGC-5 high sugar model by 7, 8-DHF | 上海市松江区中心医院（上海交通大学附属第一人民医院松江分院） | 2024-08-06 | — | — | CN | disclosed |
| CN-109574975-B | Crystal form of 7,8-dihydroxyflavone derivative, and preparation method and application thereof | 上海博芮健制药有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116064611-A | Non-human animals comprising a humanized TRKB locus | 瑞泽恩制药公司 | 2023-05-05 | — | — | CN | disclosed |
| WO-2023288069-A1 | METHODS OF USING SUBSTITUTED FLAVONES FOR TREATING BONE DISORDERS | EMORY UNIVERSITY (US) | 2023-01-19 | — | — | WO | disclosed |
| CN-111655031-B | Non-human animals comprising humanized TRKB loci | 瑞泽恩制药公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-115252600-A | Xanthine oxidase inhibitor targeting intestinal flora and application thereof | 华南农业大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-115025075-A | New application of FK3 medicine | 沈阳药科大学 | 2022-09-09 | — | — | CN | disclosed |
| CN-114870023-A | Slow-release optic nerve protection drug nano synthetic material and preparation method and application thereof | 成都市第三人民医院 | 2022-08-09 | — | — | CN | disclosed |
| CN-114641317-A | 7, 8-dihydroxyflavone composite nano biomaterial with high bioavailability as well as preparation method and application thereof | 杭州尤美特科技有限公司 | 2022-06-17 | — | — | CN | disclosed |
| US-20220031641-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING COGNITIVE DYSFUNCTION | PHARMATROPHIX, INC. | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220031641-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING COGNITIVE DYSFUNCTION | CHRM3, CHAT, CHRM5 | TERT 2814/4885MAPT 451/4885HPGD 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.