Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18885276 | 0.84 | CNR2 (0.67) | CNR2KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL19591984 | 0.83 | POLB (0.76) | CNR2KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL6136364 | 0.81 | CNR2 (0.58) | CNR2KMT2AL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL6136330 | 0.80 | CNR2 (0.61) | CNR2KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL6136328 | 0.80 | CNR2 (0.61) | CNR2KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL12835529 | 0.80 | CNR2 (0.61) | CNR2KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL5327587 | 0.79 | ALDH1A1 (0.74) | CNR2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL19523041 | 0.79 | CNR2 (0.59) | CNR2KMT2AL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL27528191 | 0.79 | CNR2 (0.59) | CNR2KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL20099754 | 0.78 | CNR2 (0.51) | CNR2KMT2APOLBALDH1A1PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9802958-B2 | Tetrahydro[1,8]naphthyridine sulfonamide and related compounds for use as agonists of RORy and the treatment of disease | LYCERA CORPORATION (US) | 2017-10-31 | — | — | US | disclosed |