Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26309847 | 0.88 | CNR2 (0.50) | CNR2KMT2APOLBALDH1A1MAPT | |
| SCHEMBL20104605 | 0.86 | CNR2 (0.48) | CNR2KMT2APOLBALDH1A1MAPT | |
| SCHEMBL20099708 | 0.84 | KMT2A (0.50) | CNR2KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL12835529 | 0.81 | CNR2 (0.61) | CNR2KMT2APOLBALDH1A1MAPT | |
| SCHEMBL19523045 | 0.78 | CNR2 (0.61) | CNR2KMT2APOLBALDH1A1PSMB8 | |
| SCHEMBL5327587 | 0.77 | ALDH1A1 (0.74) | CNR2KMT2APOLBALDH1A1MAPT | |
| SCHEMBL18885276 | 0.76 | CNR2 (0.67) | CNR2KMT2APOLBALDH1A1PSMB8 | |
| SCHEMBL20130631 | 0.74 | ALDH1A1 (0.49) | CNR2KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL7151264 | 0.74 | NPC1 (0.50) | CNR2KMT2APOLBALDH1A1MAPT | |
| SCHEMBL12809523 | 0.73 | POLB (0.61) | CNR2KMT2APOLBALDH1A1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532486-B1 | ANTIBODY-COUPLED CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2021-09-22 | — | — | EP | disclosed |
| WO-2018081370-A1 | ANTIBODY-COUPLED CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |
| WO-2018081367-A1 | CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |