Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.68 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.66 |
| ▸ | WNT3A | P56704 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5981843 | 0.86 | ADAM17 (0.66) | ADAM17CTNNB1WNT3AALDH1A1ATM | |
| SCHEMBL4852469 | 0.86 | ADAM17 (0.66) | ADAM17CTNNB1WNT3AALDH1A1ATM | |
| SCHEMBL1563151 | 0.86 | GABRA1 (0.74) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL27611369 | 0.85 | ADAM17 (0.57) | ADAM17CTNNB1WNT3AALDH1A1ATM | |
| SCHEMBL8959866 | 0.85 | GABRA1 (0.72) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL8959575 | 0.85 | GABRA1 (0.72) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL8959628 | 0.85 | GABRA1 (0.72) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL8960031 | 0.85 | GABRA1 (0.72) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL8077164 | 0.85 | GABRA1 (0.72) | ADAM17CTNNB1WNT3AGABRA1GABRB2 | |
| SCHEMBL4859074 | 0.85 | CTNNB1 (0.67) | ADAM17CTNNB1WNT3AALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053941-A1 | IDO Inhibitors | NEWLINK GENETICS (US) | 2011-03-03 | — | — | US | disclosed |
| WO-2009073620-A2 | IDO INHIBITORS | NEWLINK GENETICS (US) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053941-A1 | IDO Inhibitors | IDO1, IDO2, INMT | ADAM17 1489/4885CTNNB1 2843/4885WNT3A 1941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.