SCHEMBL12839633

SCHEMBL12839633

CCCc1nc(-c2ccc(OC)cc2)cnc1NC(=O)Cc1ccc(F)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.48
KMT2A Q03164 6/20 0.46
MEN1 O00255 3/20 0.46
ALDH1A1 P00352 4/20 0.45
MAPT P10636 2/20 0.45
ROCK1 Q13464 1/20 0.45
APP P05067 1/20 0.45
EGFR P00533 1/20 0.44
ERBB2 P04626 1/20 0.44
MET P08581 2/20 0.44
WNT3A P56704 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
KDM4E B2RXH2 3/20 0.43
NPC1 O15118 2/20 0.43
HPGD P15428 2/20 0.43
RAB9A P51151 2/20 0.43
ADRB2 P07550 1/20 0.43
LMNA P02545 1/20 0.43
MAPK8 P45983 1/20 0.43
KLK7 P49862 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12840473 0.93 KMT2A (0.50) TP53KMT2AMEN1ALDH1A1ROCK1
SCHEMBL12838977 0.92 SMN1; SMN2 (0.47) TP53KMT2AMEN1ALDH1A1MAPT
SCHEMBL12839629 0.91 MTOR (0.46) KMT2AMEN1ALDH1A1MAPTROCK1
SCHEMBL12839635 0.90 MEN1 (0.50) TP53KMT2AMEN1ALDH1A1MAPT
SCHEMBL12839630 0.90 ALDH1A1 (0.45) KMT2AMEN1ALDH1A1MAPTROCK1
SCHEMBL12839631 0.90 ALDH1A1 (0.46) TP53KMT2AMEN1ALDH1A1MAPT
SCHEMBL12840059 0.90 ALDH1A1 (0.51) KMT2AMEN1ALDH1A1MAPTAPP
SCHEMBL12839632 0.90 KMT2A (0.52) KMT2AMEN1ALDH1A1MAPTROCK1
SCHEMBL12840420 0.89 KMT2A (0.47) KMT2AMEN1ALDH1A1ROCK1MET
SCHEMBL12839104 0.89 KMT2A (0.47) KMT2AMEN1ALDH1A1ROCK1MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110070656-A1 Fluorescent Proteins JNC CORPORATION (JP) 2011-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110070656-A1 Fluorescent Proteins CACYBP, CHLSN, LCP2 TP53 3223/4885KMT2A 4653/4885MEN1 3926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.