SCHEMBL12839635

SCHEMBL12839635

CCCc1nc(-c2ccc(OC)cc2)cnc1NC(=O)Cc1ccc(Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
TP53 P04637 1/20 0.50
KDR P35968 2/20 0.48
MAPT P10636 2/20 0.47
POLB P06746 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
CNR2 P34972 1/20 0.46
CSNK1D P48730 1/20 0.46
NOD2 Q9HC29 1/20 0.45
ALDH1A1 P00352 3/20 0.45
ROCK1 Q13464 1/20 0.45
APP P05067 1/20 0.45
EGFR P00533 1/20 0.44
ERBB2 P04626 1/20 0.44
WNT3A P56704 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 1/20 0.43
NPC1 O15118 1/20 0.43
ADRB2 P07550 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12838975 0.92 MEN1 (0.52) MEN1KMT2ATP53KDRMAPT
SCHEMBL12839629 0.91 MTOR (0.46) MEN1KMT2AMAPTPOLBL3MBTL1
SCHEMBL12839633 0.90 TP53 (0.48) MEN1KMT2ATP53MAPTALDH1A1
SCHEMBL12839631 0.90 ALDH1A1 (0.46) MEN1KMT2ATP53MAPTPOLB
SCHEMBL12839630 0.90 ALDH1A1 (0.45) MEN1KMT2AMAPTNOD2ALDH1A1
SCHEMBL12840059 0.90 ALDH1A1 (0.51) MEN1KMT2AMAPTL3MBTL1CNR2
SCHEMBL12838524 0.90 APP (0.49) MEN1KMT2ATP53KDRMAPT
SCHEMBL12839102 0.89 RORC (0.44) MEN1KMT2ATP53ROCK1NPC1
SCHEMBL13068290 0.88 RORC (0.43) MEN1KMT2ATP53ALDH1A1NPC1
SCHEMBL12840474 0.88 KMT2A (0.46) MEN1KMT2ATP53MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110070656-A1 Fluorescent Proteins JNC CORPORATION (JP) 2011-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110070656-A1 Fluorescent Proteins CACYBP, CHLSN, LCP2 MEN1 3926/4885KMT2A 4653/4885TP53 3223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.