Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29682135 | 0.84 | L3MBTL1 (0.80) | L3MBTL1SMN1; SMN2POLBGLAPTGDR2 | |
| SCHEMBL340762 | 0.84 | L3MBTL1 (0.80) | L3MBTL1SMN1; SMN2POLBGLAPTGDR2 | |
| SCHEMBL13730248 | 0.83 | SMN1; SMN2 (0.42) | L3MBTL1SMN1; SMN2POLBGLAPTGDR2 | |
| Ammonia Solution, Strong SCHEMBL28240461 | 0.82 | L3MBTL1 (0.77) | L3MBTL1SMN1; SMN2POLBGLAPTGDR2 | |
| SCHEMBL28288419 | 0.82 | MAPT (0.52) | L3MBTL1SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL1508488 | 0.82 | L3MBTL1 (0.61) | L3MBTL1SMN1; SMN2POLBGLAPTGDR2 | |
| SCHEMBL1577431 | 0.82 | RXRA (0.59) | L3MBTL1SMN1; SMN2POLBGLAPTGDR2 | |
| SCHEMBL30680095 | 0.82 | RXRA (0.59) | L3MBTL1SMN1; SMN2POLBGLAPTGDR2 | |
| SCHEMBL10030744 | 0.81 | AR (0.51) | L3MBTL1SMN1; SMN2POLBGLAKDM4E | |
| SCHEMBL7333637 | 0.79 | CXCL8 (0.55) | L3MBTL1SMN1; SMN2TDP1MEN1S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012147107-A2 | NOVEL & IMPROVED PROCESSES FOR THE PREPARATION OF INDOLINE DERIVATIVES AND ITS PHARMACEUTICAL COMPOSITION | MSN LABORATORIES LIMITED (IN) | 2012-11-01 | — | — | WO | claimed |
| WO-2012147107-A2 | NOVEL & IMPROVED PROCESSES FOR THE PREPARATION OF INDOLINE DERIVATIVES AND ITS PHARMACEUTICAL COMPOSITION | MSN LABORATORIES LIMITED (IN) | 2012-11-01 | — | — | WO | disclosed |
| WO-2011030356-A2 | PROCESS FOR THE PREPARATION OF INDOLINE DERIVATIVES AND THEIR INTERMEDIATES THEREOF | SANDOZ AG (IN) | 2011-03-17 | — | — | WO | disclosed |