Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12842879 | 0.92 | CYP1A2 (0.36) | SMN1; SMN2CA2ALDH1A1POLBTYR | |
| SCHEMBL12956770 | 0.91 | GABRA1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL13972376 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2CA2ALDH1A1POLBTYR | |
| SCHEMBL12842302 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2CA2ALDH1A1POLBTYR | |
| SCHEMBL12842875 | 0.87 | GABRA1 (0.35) | CYP2C9CYP2C19GABRA1GABRB2 | |
| SCHEMBL12842865 | 0.84 | ALDH1A1 (0.41) | SMN1; SMN2CA2ALDH1A1POLBTYR | |
| SCHEMBL12843526 | 0.83 | ALDH1A1 (0.39) | SMN1; SMN2CA2ALDH1A1POLBTYR | |
| SCHEMBL12843171 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2CA2ALDH1A1POLBTYR | |
| SCHEMBL12843522 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2CA2ALDH1A1POLBTYR | |
| SCHEMBL12843549 | 0.81 | TRPA1 (0.33) | ALDH1A1HSD17B10GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915455-B2 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-03-29 | — | — | US | disclosed |