Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13972127 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL12842876 | 0.87 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL12842298 | 0.85 | LMNA (0.30) | SMN1; SMN2 | |
| SCHEMBL13972150 | 0.84 | TRPA1 (0.31) | ALDH1A1HSD17B10GAATSHR | |
| SCHEMBL12843211 | 0.83 | PTGER4 (0.32) | — | |
| SCHEMBL13972153 | 0.82 | GABRA1 (0.30) | GABRA1GABRB2 | |
| SCHEMBL14522103 | 0.82 | CYP1A2 (0.32) | CYP2C9CYP2C19CYP1A2CYP3A4TSHR | |
| SCHEMBL12771782 | 0.82 | HSPA5 (0.37) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL12842300 | 0.81 | GABRA1 (0.32) | HSPA5GABRA1GABRB2 | |
| SCHEMBL12842865 | 0.81 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915455-B2 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-03-29 | — | — | US | disclosed |