Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12778370 | 0.80 | THRA (0.49) | THRATHRBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL12778374 | 0.80 | PDK2 (0.43) | THRATHRBCYP1A2CYP2C19PPARD | |
| SCHEMBL8257891 | 0.78 | MAOA (0.39) | THRATHRBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL21678024 | 0.76 | PPARA (0.48) | PPARDPPARA | |
| SCHEMBL12762091 | 0.76 | NQO1 (0.46) | CYP3A4LMNAL3MBTL1 | |
| SCHEMBL24935357 | 0.75 | HDAC1 (0.44) | THRATHRBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL12059085 | 0.73 | TSHR (0.50) | CYP1A2 | |
| SCHEMBL5543083 | 0.73 | MCL1 (0.56) | PPARDLMNAL3MBTL1PPARA | |
| SCHEMBL16723455 | 0.73 | LMNA (0.46) | CYP2C19CYP2C9PPARDLMNARHEB | |
| SCHEMBL17138150 | 0.72 | MTNR1A (0.46) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110052534-A1 | Imidazopyridazine Compounds for Treating Viral Infections | LEIVERS MARTIN | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110052534-A1 | Imidazopyridazine Compounds for Treating Viral Infections | ACE, ACE2, TPMT | THRA 3193/4885THRB 3650/4885CYP1A2 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.