Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1696544 | 1.00 | HSD11B1 (0.48) | HSD11B1SCN9AGLAALDH1A1MAPT | |
| SCHEMBL1036632 | 0.87 | HSD11B1 (0.48) | HSD11B1SCN9AGLAALDH1A1MAPT | |
| SCHEMBL17188550 | 0.87 | HSD11B1 (0.48) | HSD11B1SCN9AGLAALDH1A1MAPT | |
| SCHEMBL15831171 | 0.86 | GLA (0.47) | HSD11B1SCN9AGLAALDH1A1MAPT | |
| SCHEMBL17050923 | 0.85 | HSD11B1 (0.39) | HSD11B1SCN9AALDH1A1MAPTMEN1 | |
| SCHEMBL18467244 | 0.84 | PRKCA (0.44) | HSD11B1SCN9AALDH1A1MAPTMEN1 | |
| SCHEMBL15432440 | 0.84 | LMNA (0.42) | HSD11B1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1035514 | 0.81 | GLA (0.43) | HSD11B1SCN9AGLAALDH1A1MAPT | |
| SCHEMBL13495293 | 0.81 | GLA (0.43) | HSD11B1SCN9AGLAALDH1A1MAPT | |
| SCHEMBL905300 | 0.80 | GLA (0.57) | GLAALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053943-A1 | CARBAMATE AND UREA INHIBITORS OF 11ß-HYDROXYSTEROID DEHYDROGENASE 1 | VITAE PHARMACEUTICALS, INC. | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053943-A1 | CARBAMATE AND UREA INHIBITORS OF 11ß-HYDROXYSTEROID DEHYDROGENASE 1 | HSD11B1, HSD11B2, HSD3B1 | HSD11B1 1/4885SCN9A 1353/4885GLA 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.