Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 7/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772407 | 0.84 | GABRA1 (0.40) | GABRA1GABRB2ALDH1A1ADRA2CADRA2B | |
| SCHEMBL6952845 | 0.81 | GABRA1 (0.59) | GABRA1GABRB2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL4079752 | 0.79 | GABRA1 (0.42) | GABRA1GABRB2ALDH1A1ADRA2CADRA2B | |
| SCHEMBL13185417 | 0.79 | MGAM (0.35) | ALDH1A1 | |
| SCHEMBL10389350 | 0.78 | GABRA1 (0.41) | GABRA1GABRB2ALDH1A1ADRA2CADRA2B | |
| SCHEMBL9843604 | 0.77 | ALDH1A1 (0.35) | GABRA1GABRB2ALDH1A1ADRA2CADRA2B | |
| SCHEMBL29763626 | 0.77 | GABRA1 (0.56) | GABRA1GABRB2ALDH1A1ADRA2CADRA2B | |
| SCHEMBL173300 | 0.77 | GABRA1 (0.56) | GABRA1GABRB2ALDH1A1ADRA2CADRA2B | |
| SCHEMBL21271561 | 0.76 | MGAM (0.37) | — | |
| SCHEMBL19437729 | 0.74 | GABRA1 (0.54) | GABRA1GABRB2ALDH1A1ADRA2CADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829841-B | A kind of organosilicon macromolecule material and preparation method thereof | 山东大学 | 2017-11-10 | — | — | CN | claimed |
| CN-104829841-B | A kind of organosilicon macromolecule material and preparation method thereof | 山东大学 | 2017-11-10 | — | — | CN | disclosed |
| US-20110052643-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110052643-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | TSLP, NFATC1, IL5 | GABRA1 1550/4885GABRB2 1380/4885ALDH1A1 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.