SCHEMBL12849035

SCHEMBL12849035

COc1cc(Br)ccc1-c1ccc(Br)cc1CO

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
PTGDR2 Q9Y5Y4 1/20 0.44
ALDH1A1 P00352 2/20 0.43
USP2 O75604 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
THRB P10828 1/20 0.43
ALOX15 P16050 1/20 0.43
CASP1 P29466 1/20 0.43
HTT P42858 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
HSD17B10 Q99714 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PDE4A P27815 1/20 0.43
PDE4B Q07343 1/20 0.43
PDE4C Q08493 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203385 0.83 PTGDR2 (0.47) MEN1KMT2APTGDR2ALDH1A1MAPT
SCHEMBL1145684 0.82 PTGDR2 (0.57) KDM4ETDP1MEN1KMT2APTGDR2
SCHEMBL30223764 0.82 PYCR1 (0.51) KDM4ETDP1MEN1KMT2APTGDR2
SCHEMBL1427602 0.82 PYCR1 (0.51) KDM4ETDP1MEN1KMT2APTGDR2
SCHEMBL12259237 0.77 ACHE (0.48) KDM4ETDP1MEN1KMT2AALDH1A1
SCHEMBL10021493 0.76 MAPT (0.53) KDM4EALDH1A1USP2GAAMAPT
SCHEMBL12798314 0.74 PTGDR2 (0.43) MEN1KMT2APTGDR2ALDH1A1MAPT
SCHEMBL293625 0.73 GAA (0.56) MEN1KMT2AALDH1A1GAAMAPT
SCHEMBL28855352 0.73 PDE4A (0.47) KDM4ETDP1MEN1KMT2APTGDR2
SCHEMBL6587067 0.73 NPC1 (0.51) PTGDR2ALDH1A1GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7898163-B2 (Partially) conjugated polymer, process for its preparation and use in electroluminescent devices CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2011-03-01 US disclosed
US-7462683-B2 Dihalide, polymer compound and method for producing the same TOKYO INSTITUTE OF TECHNOLOGY (JP) 2008-12-09 US disclosed