Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 5/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284969 | 1.00 | NPC1 (0.36) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1285743 | 0.93 | MAOA (0.36) | MAPTSMN1; SMN2PIM1MAOAIDO1 | |
| SCHEMBL1285742 | 0.93 | MAOA (0.36) | MAPTSMN1; SMN2PIM1MAOAIDO1 | |
| SCHEMBL1285076 | 0.89 | LMNA (0.38) | NPC1TP53MAPTRAB9APIM1 | |
| SCHEMBL1285073 | 0.89 | LMNA (0.38) | NPC1TP53MAPTRAB9APIM1 | |
| SCHEMBL1285494 | 0.88 | LMNA (0.37) | MAPTPIM1MAOAUSP2MMP2 | |
| SCHEMBL1285424 | 0.88 | MAOA (0.34) | TP53SMN1; SMN2PIM1MAOAUSP2 | |
| SCHEMBL1285425 | 0.88 | MAOA (0.34) | TP53SMN1; SMN2PIM1MAOAUSP2 | |
| SCHEMBL1285495 | 0.88 | LMNA (0.37) | MAPTPIM1MAOAUSP2MMP2 | |
| SCHEMBL1285041 | 0.87 | MAPT (0.41) | NPC1TP53MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383843-B2 | Method for preparing a coumarin compound, chromene compound, and method for preparing a chromene compound | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-02-26 | — | — | US | disclosed |
| US-20120088923-A1 | METHOD FOR PREPARING A COUMARIN COMPOUND, CHROMENE COMPOUND, AND METHOD FOR PREPARING A CHROMENE COMPOUND | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088923-A1 | METHOD FOR PREPARING A COUMARIN COMPOUND, CHROMENE COMPOUND, AND METHOD FOR PREPARING A CHROMENE COMPOUND | CYP3A7, CYP2A7, F7 | NPC1 548/4885TP53 1672/4885MAPT 4232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.