Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067335 | 0.70 | BRPF1 (0.33) | HTR2AHTR2CHRH1ADRA2AADRA2B | |
| SCHEMBL1996858 | 0.70 | BRPF1 (0.33) | HTR2AHTR2CHRH1ADRA2AADRA2B | |
| SCHEMBL9578742 | 0.70 | — | — | |
| SCHEMBL29925103 | 0.70 | HDAC4 (0.50) | ACHEHTR2AHTR2CHRH1ADRA2A | |
| SCHEMBL1105797 | 0.70 | HDAC4 (0.50) | ACHEHTR2AHTR2CHRH1ADRA2A | |
| SCHEMBL22879391 | 0.70 | ACHE (0.37) | ACHEHTR2AHTR2CHRH1ADRA2A | |
| Iodide SCHEMBL28367716 | 0.68 | HDAC4 (0.48) | ACHEHTR2AHTR2CHRH1ADRA2A | |
| SCHEMBL14422967 | 0.68 | DRD2 (0.31) | — | |
| SCHEMBL22044322 | 0.66 | DRD1 (0.34) | HTR2AHTR2CHRH1ADRA2AADRA2B | |
| SCHEMBL25835838 | 0.66 | SETD7 (0.37) | HTR2AHTR2CHRH1ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031330-A1 | AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS | ENZO LIFE SCIENCES, INC. (US) | 2011-03-17 | — | — | WO | disclosed |