Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.34 |
| ▸ | GLP1R | P43220 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ENO1 | P06733 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12655854 | 1.00 | MEN1 (0.40) | MEN1KMT2ACES2CA2NCF1 | |
| SCHEMBL16426613 | 1.00 | MEN1 (0.40) | MEN1KMT2ACES2CA2NCF1 | |
| SCHEMBL13035784 | 1.00 | MEN1 (0.40) | MEN1KMT2ACES2CA2NCF1 | |
| SCHEMBL12666252 | 0.97 | MEN1 (0.40) | MEN1KMT2ACES2CA2NCF1 | |
| SCHEMBL12666247 | 0.97 | MEN1 (0.40) | MEN1KMT2ACES2CA2NCF1 | |
| SCHEMBL12666251 | 0.97 | MEN1 (0.40) | MEN1KMT2ACES2CA2NCF1 | |
| SCHEMBL13649533 | 0.97 | MEN1 (0.40) | MEN1KMT2ACES2CA2NCF1 | |
| SCHEMBL24040332 | 0.91 | MEN1 (0.41) | MEN1KMT2ACA2NCF1CA12 | |
| SCHEMBL17029409 | 0.90 | CA2 (0.38) | MEN1KMT2ACES2CA2CA12 | |
| SCHEMBL26376485 | 0.89 | CES2 (0.44) | MEN1KMT2ACES2GLP1RSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011033068-A1 | LONG-ACTING Y2 RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2011-03-24 | — | — | WO | disclosed |
| WO-2009138511-A1 | LONG-ACTING Y2 AND/OR Y4 RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2009-11-19 | — | — | WO | disclosed |