Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ENO1 | P06733 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12666251 | 1.00 | MEN1 (0.40) | MEN1KMT2ACA2NCF1SLC9A3 | |
| SCHEMBL13649533 | 1.00 | MEN1 (0.40) | MEN1KMT2ACA2NCF1SLC9A3 | |
| SCHEMBL12666252 | 1.00 | MEN1 (0.40) | MEN1KMT2ACA2NCF1SLC9A3 | |
| SCHEMBL12655854 | 0.97 | MEN1 (0.40) | MEN1KMT2ACA2NCF1SLC9A3 | |
| SCHEMBL13035784 | 0.97 | MEN1 (0.40) | MEN1KMT2ACA2NCF1SLC9A3 | |
| SCHEMBL16426613 | 0.97 | MEN1 (0.40) | MEN1KMT2ACA2NCF1SLC9A3 | |
| SCHEMBL12850137 | 0.97 | MEN1 (0.40) | MEN1KMT2ACA2NCF1SLC9A3 | |
| SCHEMBL20017289 | 0.91 | MEN1 (0.41) | MEN1KMT2ACA2NCF1SLC9A3 | |
| SCHEMBL24393831 | 0.90 | CES2 (0.39) | MEN1KMT2ACA2NCF1SLC9A3 | |
| SCHEMBL24040332 | 0.88 | MEN1 (0.41) | MEN1KMT2ACA2NCF1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10180426-B2 | Quantification of single target molecules in histological samples | DAKO DENMARK A/S (DK) | 2019-01-15 | — | — | US | disclosed |
| US-9688737-B2 | Protease stabilized acylated insulin analogues | NOVO NORDISK A/S (DK) | 2017-06-27 | — | — | US | disclosed |
| US-20150210747-A1 | PROTEASE STABILIZED ACYLATED INSULIN ANALOGUES | NOVO NORDISK AS (DK) | 2015-07-30 | — | — | US | disclosed |
| US-20150210748-A1 | PROTEASE STABILIZED ACYLATED INSULIN ANALOGUES | NOVO NORDISK AS (DK) | 2015-07-30 | — | — | US | disclosed |
| US-9045560-B2 | Protease stabilized, acylated insulin analogues | NOVO NORDISK A/S (DK) | 2015-06-02 | — | — | US | disclosed |
| US-20150148521-A1 | INSULINS WITH AN ACYL MOIETY COMPRISING REPEATING UNITS OF ALKYLENE GLYCOL CONTAINING AMINO ACIDS | NOVO NORDISK AS (DK) | 2015-05-28 | — | — | US | disclosed |
| US-9035020-B1 | Insulins with an acyl moiety comprising repeating units of alkylene glycol containing amino acids | NOVO NORDISK A/S (DK) | 2015-05-19 | — | — | US | disclosed |
| US-8962794-B2 | Insulins with an acyl moiety comprising repeating units of alkylene glycol containing amino acids | NOVO NORDISK A/S (DK) | 2015-02-24 | — | — | US | disclosed |
| US-20140073564-A1 | PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES | NOVO NORDISK A/S (DK) | 2014-03-13 | — | — | US | disclosed |
| US-20110105720-A1 | PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES | NOVO NORDISK A/S (DK) | 2011-05-05 | — | — | US | disclosed |
| US-20110098439-A1 | INSULINS WITH AN ACYL MOIETY COMPRISING REPEATING UNITS OF ALKYLENE GLYCOL CONTAINING AMINO ACIDS | NOVO NORDISK A/S (DK) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210747-A1 | PROTEASE STABILIZED ACYLATED INSULIN ANALOGUES | IAPP, IDE, LIPE | MEN1 560/4885KMT2A 2426/4885CA2 2698/4885 |
| US-20110105720-A1 | PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES | IAPP, IDE, LIPE | MEN1 535/4885KMT2A 2298/4885CA2 2485/4885 |
| US-20140073564-A1 | PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES | IAPP, IDE, LIPE | MEN1 535/4885KMT2A 2298/4885CA2 2485/4885 |
| US-20150148521-A1 | INSULINS WITH AN ACYL MOIETY COMPRISING REPEATING UNITS OF ALKYLENE GLYCOL CONTAINING AMINO ACIDS | IAPP, INSR, IGF1R | MEN1 430/4885KMT2A 977/4885CA2 4360/4885 |
| US-20110098439-A1 | INSULINS WITH AN ACYL MOIETY COMPRISING REPEATING UNITS OF ALKYLENE GLYCOL CONTAINING AMINO ACIDS | IAPP, INSR, IGF1R | MEN1 430/4885KMT2A 977/4885CA2 4360/4885 |
| US-20150210748-A1 | PROTEASE STABILIZED ACYLATED INSULIN ANALOGUES | IAPP, IDE, LIPE | MEN1 560/4885KMT2A 2426/4885CA2 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.