Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 8/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12655854 | 0.90 | MEN1 (0.40) | CA2CA12CA1CA4CA9 | |
| SCHEMBL16426613 | 0.90 | MEN1 (0.40) | CA2CA12CA1CA4CA9 | |
| SCHEMBL12850137 | 0.90 | MEN1 (0.40) | CA2CA12CA1CA4CA9 | |
| SCHEMBL13035784 | 0.90 | MEN1 (0.40) | CA2CA12CA1CA4CA9 | |
| SCHEMBL19369891 | 0.90 | SLC6A5 (0.42) | CA2CA12CA1CA4CA9 | |
| SCHEMBL12666251 | 0.87 | MEN1 (0.40) | CA2CA12CA1CA4CA9 | |
| SCHEMBL12666252 | 0.87 | MEN1 (0.40) | CA2CA12CA1CA4CA9 | |
| SCHEMBL12666247 | 0.87 | MEN1 (0.40) | CA2CA12CA1CA4CA9 | |
| SCHEMBL12147645 | 0.87 | TSHR (0.47) | CA2CA12CA1CA4CA9 | |
| SCHEMBL13649533 | 0.87 | MEN1 (0.40) | CA2CA12CA1CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2910569-A1 | Protease stabilized, acylated insulin analogues | Novo Nordisk A/S (DK) | 2015-08-26 | — | — | EP | disclosed |
| EP-2910570-A1 | Protease stabilized, acylated insulin analogues | Novo Nordisk A/S (DK) | 2015-08-26 | — | — | EP | disclosed |
| EP-2910571-A1 | Protease stabilized, acylated insulin analogues | Novo Nordisk A/S (DK) | 2015-08-26 | — | — | EP | disclosed |