Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10029426 | 0.77 | ALDH1A1 (0.33) | KDM4EALDH1A1RAPGEF4 | |
| SCHEMBL7760842 | 0.76 | ALDH1A1 (0.33) | KDM4EALDH1A1RAPGEF4 | |
| SCHEMBL17532970 | 0.76 | ALDH1A1 (0.32) | KDM4EALDH1A1RAPGEF4 | |
| SCHEMBL12852204 | 0.74 | KDM4E (0.32) | KDM4EALDH1A1RAPGEF4 | |
| SCHEMBL12852210 | 0.74 | KDM4E (0.32) | KDM4EALDH1A1RAPGEF4 | |
| SCHEMBL22825416 | 0.72 | KDM4E (0.31) | KDM4EALDH1A1RAPGEF4 | |
| SCHEMBL21580600 | 0.72 | RAPGEF4 (0.34) | KDM4EALDH1A1RAPGEF4 | |
| SCHEMBL21065371 | 0.72 | KDM4E (0.31) | KDM4EALDH1A1RAPGEF4 | |
| SCHEMBL18198913 | 0.72 | KDM4E (0.31) | KDM4EALDH1A1RAPGEF4 | |
| SCHEMBL15069120 | 0.72 | KDM4E (0.31) | KDM4EALDH1A1RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8278456-B2 | Synthesis and stabilization of neutral compounds with homonuclear bonds | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-10-02 | — | — | US | disclosed |
| US-8278456-B2 | Synthesis and stabilization of neutral compounds with homonuclear bonds | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-10-02 | — | — | US | disclosed |
| US-20100041895-A1 | Synthesis and Stabilization of Neutral Compounds with Homonuclear Bonds | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2010-02-18 | — | — | US | disclosed |
| US-20100041895-A1 | Synthesis and Stabilization of Neutral Compounds with Homonuclear Bonds | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041895-A1 | Synthesis and Stabilization of Neutral Compounds with Homonuclear Bonds | NCL, NCLN, NES | KDM4E 3953/4885ALDH1A1 4272/4885RAPGEF4 2954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.