Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29669930 | 1.00 | IDO1 (0.50) | IDO1CA1CA2PDE10AGAA | |
| SCHEMBL20776810 | 0.89 | APP (0.51) | IDO1CA1CA2PDE10AGAA | |
| SCHEMBL5162262 | 0.88 | CA1 (0.45) | CA1CA2PDE10AGAAALDH1A1 | |
| SCHEMBL109612 | 0.86 | IDO1 (0.49) | IDO1CA1CA2PDE10AGAA | |
| SCHEMBL30086965 | 0.86 | IDO1 (0.49) | IDO1CA1CA2PDE10AGAA | |
| SCHEMBL2601944 | 0.86 | GAA (0.52) | IDO1GAAALDH1A1MAPTKDM4E | |
| Water SCHEMBL9794540 | 0.85 | IDO1 (0.47) | IDO1CA1CA2PDE10AGAA | |
| Hydrochloric Acid SCHEMBL9794562 | 0.85 | GAA (0.47) | IDO1GAAALDH1A1MAPTKDM4E | |
| SCHEMBL6251622 | 0.84 | GAA (0.45) | CA1CA2PDE10AGAAALDH1A1 | |
| SCHEMBL29393081 | 0.84 | ALDH1A1 (0.46) | IDO1GAAALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 902 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7413579-B2 | Method for dyeing fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-08-19 | — | — | US | claimed |
| EP-1909913-A1 | METHOD FOR QUICKLY CONCEALING THE ROOTS OF HAIR THAT HAVE GROWN AFTER THE HAIR HAS BEEN DYED | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-04-16 | — | — | EP | claimed |
| EP-1759735-B1 | Method of selectively dyeing portions of hair | HENKEL KGAA (DE) | 2007-12-05 | — | — | EP | claimed |
| EP-1453477-B1 | DEVELOPER-COUPLER COMBINATION CONTAINING 2,4-DICHLORO-3-AMINOPHENOL | HENKEL KGAA (DE) | 2007-10-17 | — | — | EP | claimed |
| EP-1789015-A1 | METHOD FOR STYLISHLY CHANGING THE COLOR OF KERATINIC FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-05-30 | — | — | EP | claimed |
| EP-1776984-A2 | Method for extending the recoloring cycles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-04-25 | — | — | EP | claimed |
| EP-1759735-A1 | Method of selectively dyeing portions of hair | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-03-07 | — | — | EP | claimed |
| WO-2007017048-A1 | METHOD FOR QUICKLY CONCEALING THE ROOTS OF HAIR THAT HAVE GROWN AFTER THE HAIR HAS BEEN DYED | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-02-15 | — | — | WO | claimed |
| US-20060265818-A1 | At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections | HENKEL KOMMANDITGESELLSCHAFT AUF AKLLEN (HENKEL KGAA) (DE) | 2006-11-30 | — | — | US | claimed |
| EP-1715836-A1 | METHOD FOR DYEING FIBRES CONTAINING KERATINE | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-11-02 | — | — | EP | claimed |
| WO-2003053385-A1 | NOVEL OXIDATION DYES COMPRISING 2,4-DICHLORO-3-AMINOPHENOL | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-07-03 | — | — | WO | claimed |
| US-20030106167-A1 | Oxidation colorant of a m-phenylenediamine and a primary intermediates of a p-phenylenediamine, a p-aminophenol binuclear primary and intermediates or pyrazole derivatives | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2003-06-12 | — | — | US | claimed |
| EP-1309540-A1 | OXIDIZING COLORANT | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-05-14 | — | — | EP | claimed |
| EP-1286646-A1 | OXIDATION DYEING METHOD FOR KERATINOUS FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-03-05 | — | — | EP | claimed |
| EP-1235550-A2 | NEW COLOURING COMBINATION | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-09-04 | — | — | EP | claimed |
| WO-2002038533-A1 | NOVEL COUPLING COMPONENTS FOR OXIDATION DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-05-16 | — | — | WO | claimed |
| WO-2002026201-A2 | OXIDATION DYES WITH 2-AMINO-5-METHYLPHENOL | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-04-04 | — | — | WO | claimed |
| WO-2002010118-A1 | OXIDIZING COLORANT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-02-07 | — | — | WO | claimed |
| WO-2001093819-A1 | OXIDATION DYEING METHOD FOR KERATINOUS FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-13 | — | — | WO | claimed |
| WO-2001041717-A2 | NEW COLOURING COMBINATION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-06-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030106167-A1 | Oxidation colorant of a m-phenylenediamine and a primary intermediates of a p-phenylenediamine, a p-aminophenol binuclear primary and intermediates or pyrazole derivatives | KRT18, PPOX, CDC73 | IDO1 2289/4885CA1 3076/4885CA2 3809/4885 |
| US-20060265818-A1 | At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections | KRT18, CUTA, PLOD2 | IDO1 125/4885CA1 328/4885CA2 603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.