SCHEMBL12855845

SCHEMBL12855845

C=Cc1ccc(C(=O)NCCCN(C)C)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.63
KDM4E B2RXH2 4/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
THRA P10827 1/20 0.52
THRB P10828 1/20 0.52
ALDH1A1 P00352 4/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NAMPT P43490 2/20 0.50
HSD17B10 Q99714 1/20 0.50
POLB P06746 3/20 0.49
ALOX15 P16050 1/20 0.49
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC10 Q969S8 1/20 0.49
HDAC11 Q96DB2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22708464 0.91 ALDH1A1 (0.58) HPGDKDM4ETHRATHRBALDH1A1
SCHEMBL10020214 0.87 HPGD (0.79) HPGDKDM4ENPC1RAB9AL3MBTL1
SCHEMBL17208800 0.87 HPGD (0.65) HPGDKDM4ENPC1RAB9AL3MBTL1
SCHEMBL26417166 0.86 MAPK1 (0.56) NPC1RAB9AL3MBTL1ALDH1A1POLB
SCHEMBL8744962 0.84 MAPK1 (0.59) NPC1RAB9AL3MBTL1ALDH1A1POLB
SCHEMBL12319407 0.82 ALDH1A1 (0.50) NPC1RAB9AL3MBTL1ALDH1A1NAMPT
SCHEMBL2120449 0.81 HPGD (0.70) HPGDKDM4ENPC1RAB9AL3MBTL1
SCHEMBL8411545 0.81 HPGD (0.70) HPGDKDM4ENPC1RAB9AL3MBTL1
SCHEMBL19832508 0.81 POLB (0.51) HPGDKDM4EALDH1A1NAMPTPOLB
SCHEMBL9511746 0.80 HPGD (0.68) HPGDKDM4ENPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8828629-B2 Black curable composition, light-shielding color filter for a solid-state imaging device and method of producing the same, solid-state imaging device, wafer level lens, and camera module FUJIFILM CORPORATION (JP) 2014-09-09 US disclosed
US-8389185-B2 Pigment dispersion, colored curable composition, color filter and method of manufacturing the same FUJIFILM CORPORATION (JP) 2013-03-05 US disclosed
US-20130028587-A1 BLACK CURABLE COMPOSITION, LIGHT-SHIELDING COLOR FILTER FOR A SOLID-STATE IMAGING DEVICE AND METHOD OF PRODUCING THE SAME, SOLID-STATE IMAGING DEVICE, WAFER LEVEL LENS, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2013-01-31 US disclosed
US-20110045412-A1 PIGMENT DISPERSION, COLORED CURABLE COMPOSITION, COLOR FILTER AND METHOD OF MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2011-02-24 US disclosed