Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.51 |
| ▸ | NAAA | Q02083 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26417166 | 0.98 | MAPK1 (0.56) | MAPK1NPC1RAB9AL3MBTL1HDAC1 | |
| SCHEMBL13593276 | 0.91 | MAPK1 (0.77) | MAPK1NPC1RAB9AHDAC1HDAC2 | |
| SCHEMBL1813428 | 0.91 | MAPK1 (0.77) | MAPK1NPC1RAB9AHDAC1HDAC2 | |
| SCHEMBL14407383 | 0.88 | ALDH1A1 (0.69) | MAPK1NPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL12319407 | 0.87 | ALDH1A1 (0.50) | MAPK1NPC1RAB9AL3MBTL1HDAC1 | |
| SCHEMBL19832508 | 0.86 | POLB (0.51) | MAPK1HDAC6HDAC4ALDH1A1TAS1R3 | |
| SCHEMBL12855845 | 0.84 | HPGD (0.63) | NPC1RAB9AL3MBTL1HDAC1HDAC2 | |
| SCHEMBL20966259 | 0.84 | CYP1A2 (0.62) | MAPK1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL27353786 | 0.84 | TAS1R3 (0.60) | NPC1RAB9AL3MBTL1NAAAALDH1A1 | |
| SCHEMBL381841 | 0.81 | TAS1R3 (0.53) | RAB9AHDAC1HDAC2ALDH1A1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754693-A2 | Novel aminophenylphosphonic acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-01-22 | — | — | EP | disclosed |