Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CD69 | Q07108 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15541243 | 0.79 | KDM4E (0.43) | SMN1; SMN2KDM4EALDH1A1CD69TSHR | |
| SCHEMBL12856706 | 0.77 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL18505803 | 0.75 | CD69 (0.36) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL20438296 | 0.74 | ELANE (0.40) | CYP2A6CD69 | |
| SCHEMBL18505802 | 0.74 | CD69 (0.36) | CD69TSHRCYP2D6 | |
| SCHEMBL13129398 | 0.74 | CD69 (0.69) | LMNAKDM4EALDH1A1HSD17B10CD69 | |
| Hydroxyamine SCHEMBL11037119 | 0.73 | CD69 (0.44) | SMN1; SMN2KDM4EALDH1A1HSD17B10CD69 | |
| SCHEMBL20121198 | 0.72 | CD69 (0.34) | CD69TSHRCYP2D6 | |
| SCHEMBL14093080 | 0.72 | CD69 (0.34) | SMN1; SMN2KDM4EALDH1A1CD69 | |
| SCHEMBL12856705 | 0.72 | SMN1; SMN2 (0.32) | LMNASMN1; SMN2CRHBPCRHR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028676-A1 | Molecular Actuators, and Methods of Use Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-02-03 | — | — | US | disclosed |
| US-7658868-B2 | Class of molecular actuators where bulk actuation mechanisms such as ion intercalation are enhanced by controllable single molecule conformational rearrangements offers promise in exhibiting large active strains at moderate stresses | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-02-09 | — | — | US | disclosed |
| US-20070215839-A1 | Molecular actuators, and methods of use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070215839-A1 | Molecular actuators, and methods of use thereof | NOD2, PIEZO1, TPR | LMNA 3835/4885SMN1; SMN2 4863/4885CRHBP 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.