Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPN | P05981 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12856706 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL12856782 | 0.84 | LMNA (0.32) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL18538300 | 0.79 | ACHE (0.39) | MEN1USP2ALDH1A1HPNCYP3A4 | |
| SCHEMBL12856719 | 0.79 | ACHE (0.39) | MEN1USP2ALDH1A1HPNCYP3A4 | |
| SCHEMBL13287042 | 0.73 | SELL (0.48) | SMN1; SMN2LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL13482001 | 0.73 | DPP4 (0.38) | SMN1; SMN2LMNAHTTGAAMEN1 | |
| SCHEMBL12856784 | 0.72 | LMNA (0.35) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL12856781 | 0.70 | GSTA1 (0.41) | LMNAALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL19762894 | 0.67 | ING2 (0.68) | SMN1; SMN2LMNAGAAMEN1USP2 | |
| SCHEMBL18538255 | 0.66 | CRHBP (0.44) | SMN1; SMN2CRHBPCRHR2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028676-A1 | Molecular Actuators, and Methods of Use Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-02-03 | — | — | US | disclosed |
| US-7658868-B2 | Class of molecular actuators where bulk actuation mechanisms such as ion intercalation are enhanced by controllable single molecule conformational rearrangements offers promise in exhibiting large active strains at moderate stresses | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-02-09 | — | — | US | disclosed |
| US-20070215839-A1 | Molecular actuators, and methods of use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070215839-A1 | Molecular actuators, and methods of use thereof | NOD2, PIEZO1, TPR | SMN1; SMN2 4863/4885LMNA 3835/4885CRHBP 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.