Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433439 | 0.95 | CXCR3 (1.00) | CXCR3CYP3A4 | |
| SCHEMBL29386766 | 0.95 | CXCR3 (1.00) | CXCR3CYP3A4 | |
| SCHEMBL335753 | 0.95 | CXCR3 (1.00) | CXCR3CYP3A4 | |
| SCHEMBL5833103 | 0.94 | CXCR3 (0.89) | CXCR3CYP3A4 | |
| SCHEMBL27015148 | 0.94 | CXCR3 (0.89) | CXCR3CYP3A4 | |
| SCHEMBL12857720 | 0.89 | CXCR3 (0.91) | CXCR3CYP3A4 | |
| SCHEMBL27015149 | 0.88 | CXCR3 (0.87) | CXCR3CYP3A4 | |
| SCHEMBL14960668 | 0.86 | CXCR3 (1.00) | CXCR3CYP3A4 | |
| SCHEMBL13151360 | 0.84 | CXCR3 (0.86) | CXCR3CYP3A4 | |
| SCHEMBL12857869 | 0.84 | CXCR3 (1.00) | CXCR3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110034487-A1 | CXCR3 ANTAGONISTS | AMGEN INC. (US) | 2011-02-10 | — | — | US | disclosed |
| US-20110034487-A1 | CXCR3 ANTAGONISTS | AMGEN INC. (US) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034487-A1 | CXCR3 ANTAGONISTS | CXCR3, CXCR1, CCR5 | CXCR3 1/4885CYP3A4 4129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.