Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13387443 | 0.93 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1NPC1RAB9AHPGD | |
| SCHEMBL13290804 | 0.87 | TSHR (0.57) | SMN1; SMN2L3MBTL1NPC1RAB9AHPGD | |
| SCHEMBL11493211 | 0.86 | FAAH (0.48) | SMN1; SMN2L3MBTL1NPC1RAB9AHPGD | |
| SCHEMBL8274236 | 0.86 | FAAH (0.47) | SMN1; SMN2L3MBTL1NPC1RAB9AHPGD | |
| SCHEMBL8356570 | 0.85 | TSHR (0.53) | SMN1; SMN2L3MBTL1NPC1RAB9AMAPK1 | |
| SCHEMBL3806764 | 0.85 | TSHR (0.53) | SMN1; SMN2L3MBTL1NPC1RAB9AMAPK1 | |
| SCHEMBL4035085 | 0.84 | MEN1 (0.46) | SMN1; SMN2MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL27904059 | 0.84 | TSHR (0.53) | SMN1; SMN2MAPK1TSHRLMNACYP1A2 | |
| SCHEMBL2746868 | 0.83 | LMNA (0.58) | SMN1; SMN2MAPK1TSHRLMNA | |
| SCHEMBL17766244 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884223-B2 | N-isopropylphenethylamine; N-(2,6-dimethoxybenzyl)1-phenethylamine; (R,R) N-(1-naphth-1-ylethyl)-1-phenethylamine; high activity; easily accessible | DSM IP ASSETS B.V. (NL) | 2011-02-08 | — | — | US | disclosed |