Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.57 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13387443 | 0.93 | SMN1; SMN2 (0.50) | TSHRESR1SMN1; SMN2MAPK1LMNA | |
| Hydrochloric Acid SCHEMBL11457826 | 0.89 | ESR1 (0.53) | TSHRESR1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL12859656 | 0.87 | SMN1; SMN2 (0.46) | TSHRESR1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL11493211 | 0.86 | FAAH (0.48) | TSHRSMN1; SMN2MAPK1LMNACYP1A2 | |
| SCHEMBL8274236 | 0.86 | FAAH (0.47) | TSHRESR1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL8356570 | 0.85 | TSHR (0.53) | TSHRSMN1; SMN2MAPK1LMNACYP1A2 | |
| SCHEMBL3806764 | 0.85 | TSHR (0.53) | TSHRSMN1; SMN2MAPK1LMNACYP1A2 | |
| SCHEMBL27904059 | 0.84 | TSHR (0.53) | TSHRESR1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL388023 | 0.83 | SMN1; SMN2 (0.60) | TSHRESR1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL2746868 | 0.83 | LMNA (0.58) | TSHRSMN1; SMN2MAPK1LMNANR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824868-B1 | CHIRAL COMPOUND SUITABLE AS A CATALYST FOR ASYMMETRIC TRANSFER HYDROGENATION | DSM IP ASSETS BV (NL) | 2010-06-02 | — | — | EP | disclosed |
| US-20080269529-A1 | Chiral Compound Suitable as a Catalyst for Asymmetric Transfer Hydrogenation | PATHEON HOLDINGS I B.V. (NL) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269529-A1 | Chiral Compound Suitable as a Catalyst for Asymmetric Transfer Hydrogenation | SLC30A6, SLC39A14, SLC30A5 | TSHR 824/4885ESR1 2668/4885SMN1; SMN2 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.