Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13387443 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL13290804 | 0.86 | TSHR (0.57) | SMN1; SMN2L3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL12859656 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1HPGDNPC1RAB9A | |
| SCHEMBL11493211 | 0.84 | FAAH (0.48) | FAAHSMN1; SMN2L3MBTL1HPGDNPC1 | |
| SCHEMBL8356570 | 0.84 | TSHR (0.53) | SMN1; SMN2L3MBTL1NPC1RAB9ATSHR | |
| SCHEMBL3806764 | 0.84 | TSHR (0.53) | SMN1; SMN2L3MBTL1NPC1RAB9ATSHR | |
| SCHEMBL512726 | 0.83 | MAPT (0.46) | SMN1; SMN2HPGDNPC1RAB9ALMNA | |
| SCHEMBL27904059 | 0.83 | TSHR (0.53) | SMN1; SMN2TSHRLMNACYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL5966959 | 0.82 | MAPT (0.45) | SMN1; SMN2HPGDNPC1RAB9ALMNA | |
| SCHEMBL2746868 | 0.82 | LMNA (0.58) | SMN1; SMN2TSHRLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006009645-A1 | METHODS OF USING MACROCYCLIC MODULATORS OF THE GHRELIN RECEPTOR | TRANZYME PHARMA, INC. (US) | 2006-01-26 | — | — | WO | disclosed |