Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606066 | 0.92 | PDK2 (0.41) | TDP1ATML3MBTL1KMOPDK2 | |
| SCHEMBL2606061 | 0.90 | PDK2 (0.45) | TDP1ATML3MBTL1KMOPDK2 | |
| SCHEMBL2606064 | 0.89 | PDK2 (0.44) | TDP1ATML3MBTL1KMOPDK2 | |
| SCHEMBL12864302 | 0.88 | PDK2 (0.46) | TDP1ATML3MBTL1PDK2THRB | |
| SCHEMBL1167840 | 0.88 | TDP1 (0.52) | TDP1ATML3MBTL1PDK2THRB | |
| SCHEMBL12864217 | 0.83 | POLB (0.47) | TDP1ATML3MBTL1PDK2HDAC8 | |
| SCHEMBL12864224 | 0.83 | CES2 (0.45) | TDP1ATML3MBTL1PDK2 | |
| SCHEMBL13649845 | 0.81 | PDK2 (0.40) | TDP1ATML3MBTL1PDK2THRB | |
| SCHEMBL10053610 | 0.81 | PDK2 (0.40) | TDP1ATML3MBTL1PDK2THRB | |
| SCHEMBL12864298 | 0.81 | BCAT2 (0.44) | TDP1ATMPDK2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023117835-A1 | ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-06-29 | — | — | WO | disclosed |
| US-8361638-B2 | Fluorine derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2013-01-29 | — | — | US | disclosed |
| US-8361638-B2 | Fluorine derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20110037027-A1 | FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20110037027-A1 | FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110037027-A1 | FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | SLCO4C1, CTCF, AFF2 | TDP1 3147/4885ATM 2324/4885L3MBTL1 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.