Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12865413 | 0.84 | FFAR1 (0.33) | FFAR4 | |
| SCHEMBL12865403 | 0.79 | FFAR1 (0.30) | FFAR4 | |
| SCHEMBL14364557 | 0.78 | — | — | |
| SCHEMBL7893616 | 0.76 | ALOX5 (0.32) | — | |
| Bromide SCHEMBL3469476 | 0.75 | ALOX5 (0.31) | — | |
| SCHEMBL10120028 | 0.74 | PTGS2 (0.41) | PTGS2TUBB1PTGS1TDP2 | |
| SCHEMBL13662924 | 0.74 | ALOX5 (0.31) | — | |
| SCHEMBL13662885 | 0.74 | ALOX5 (0.31) | — | |
| SCHEMBL12583177 | 0.71 | GPR84 (0.32) | — | |
| SCHEMBL548087 | 0.71 | CD274 (0.46) | PTGS2CD274TUBB1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507669-B2 | Optically active dibenzazepine derivatives | NIPPON SODA CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20110034688-A1 | OPTICALLY ACTIVE DIBENZAZEPINE DERIVATIVES | NIPPON SODA CO., LTD. (JP) | 2011-02-10 | — | — | US | disclosed |
| EP-2264038-A1 | OPTICALLY ACTIVE DIBENZAZEPINE DERIVATIVES | Nippon Soda Co., Ltd. (JP) | 2010-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034688-A1 | OPTICALLY ACTIVE DIBENZAZEPINE DERIVATIVES | DRD1, DRD4, DRD2 | MGLL 4238/4885PTGS2 4206/4885CD274 2475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.