Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17400863 | 0.82 | ERN1 (0.31) | ALOX15ALOX12 | |
| SCHEMBL1765685 | 0.81 | TRPA1 (0.40) | ALOX15ALDH1A1KDM4EGAAMAPK1 | |
| SCHEMBL6062069 | 0.79 | ALDH1A1 (0.41) | ALOX15ALDH1A1KDM4EGAAPOLB | |
| SCHEMBL5872088 | 0.79 | ALOX15 (0.39) | ALOX15ALDH1A1KDM4EGAARECQL | |
| SCHEMBL16815430 | 0.75 | CYP3A4 (0.42) | ALOX15ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL2602667 | 0.75 | ESR1 (0.36) | ALOX15ALDH1A1KDM4EGAATRPA1 | |
| SCHEMBL10157241 | 0.75 | ALOX15 (0.41) | ALOX15ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL29979071 | 0.75 | ESR1 (0.36) | ALOX15ALDH1A1KDM4EGAATRPA1 | |
| SCHEMBL28562792 | 0.74 | KDM4E (0.46) | ALOX15ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL29380074 | 0.73 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507669-B2 | Optically active dibenzazepine derivatives | NIPPON SODA CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8507669-B2 | Optically active dibenzazepine derivatives | NIPPON SODA CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8283501-B2 | Optically active 2,2′-biphenol derivative and production method of same | NIPPON SODA CO., LTD. (JP) | 2012-10-09 | — | — | US | disclosed |
| US-8283501-B2 | Optically active 2,2′-biphenol derivative and production method of same | NIPPON SODA CO., LTD. (JP) | 2012-10-09 | — | — | US | disclosed |
| US-20110034688-A1 | OPTICALLY ACTIVE DIBENZAZEPINE DERIVATIVES | NIPPON SODA CO., LTD. (JP) | 2011-02-10 | — | — | US | disclosed |
| US-20110034688-A1 | OPTICALLY ACTIVE DIBENZAZEPINE DERIVATIVES | NIPPON SODA CO., LTD. (JP) | 2011-02-10 | — | — | US | disclosed |
| US-20100280284-A1 | OPTICALLY ACTIVE 2,2'-BIPHENOL DERIVATIVE AND PRODUCTION METHOD OF SAME | NIPPON SODA CO., LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
| US-20100280284-A1 | OPTICALLY ACTIVE 2,2'-BIPHENOL DERIVATIVE AND PRODUCTION METHOD OF SAME | NIPPON SODA CO., LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034688-A1 | OPTICALLY ACTIVE DIBENZAZEPINE DERIVATIVES | DRD1, DRD4, DRD2 | ALOX15 2229/4885ALDH1A1 935/4885KDM4E 1319/4885 |
| US-20100280284-A1 | OPTICALLY ACTIVE 2,2'-BIPHENOL DERIVATIVE AND PRODUCTION METHOD OF SAME | SQLE, CYP2J2, CYP24A1 | ALOX15 134/4885ALDH1A1 222/4885KDM4E 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.