Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3359993 | 0.83 | POLB (0.48) | TSHRCASP1PDE10ATRPA1ALDH1A1 | |
| SCHEMBL4968725 | 0.81 | PDE10A (0.54) | TSHRCASP1PDE10AALDH1A1HSD17B10 | |
| SCHEMBL31634585 | 0.81 | PDE10A (0.54) | TSHRCASP1PDE10AALDH1A1HSD17B10 | |
| SCHEMBL3371394 | 0.79 | CD44 (0.44) | TSHRCASP1PDE10ATRPA1ALDH1A1 | |
| SCHEMBL31495833 | 0.79 | PDE10A (0.52) | TSHRCASP1PDE10ATRPA1ALDH1A1 | |
| SCHEMBL118836 | 0.79 | TSHR (0.46) | TSHRCASP1PDE10ATRPA1ALDH1A1 | |
| SCHEMBL632398 | 0.77 | ALDH1A1 (0.42) | TSHRPDE10AALDH1A1HSD17B10ALOX15 | |
| SCHEMBL25370491 | 0.75 | ALDH1A1 (0.40) | TSHRCASP1PDE10ATRPA1ALDH1A1 | |
| SCHEMBL3790991 | 0.75 | ALDH1A1 (0.47) | TSHRCASP1PDE10AALDH1A1HSD17B10 | |
| SCHEMBL22363080 | 0.75 | TSHR (0.43) | TSHRCASP1PDE10ATRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8471043-B2 | Platensimycin derivatives, their intermediates, and process for preparing the same, and new process for preparing platensimycin | SNU R&DB FOUNDATION (KR) | 2013-06-25 | — | — | US | disclosed |
| US-20110028741-A1 | Novel Platensimycin Derivatives, Their Intermediates, and Process for Preparing the Same, and New Process for Preparing Platensimycin | SNU R&DB FOUNDATION (KR) | 2011-02-03 | — | — | US | disclosed |
| US-20110028741-A1 | Novel Platensimycin Derivatives, Their Intermediates, and Process for Preparing the Same, and New Process for Preparing Platensimycin | SNU R&DB FOUNDATION (KR) | 2011-02-03 | — | — | US | disclosed |
| CN-1517794-A | Resist composition | 三菱瓦斯化学株式会社 | 2004-08-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028741-A1 | Novel Platensimycin Derivatives, Their Intermediates, and Process for Preparing the Same, and New Process for Preparing Platensimycin | RPN2, RPN1, DHPS | TSHR 3867/4885CASP1 1636/4885PDE10A 3726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.