Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12871773 | 0.87 | OPRL1 (0.41) | OPRL1KCNH2CYP17A1CYP1A2TRPV1 | |
| SCHEMBL12871661 | 0.83 | RBP4 (0.36) | OPRL1KCNH2CYP17A1CYP1A2 | |
| SCHEMBL12871683 | 0.82 | OPRL1 (0.36) | OPRL1KCNH2CYP17A1CYP1A2 | |
| SCHEMBL12871679 | 0.82 | KDM4E (0.47) | OPRL1HSD11B1TRPV1ALDH1A1 | |
| SCHEMBL13105266 | 0.80 | CYP17A1 (0.40) | OPRL1KCNH2CYP17A1CYP1A2HSD11B1 | |
| SCHEMBL12871664 | 0.79 | MALT1 (0.37) | OPRL1KCNH2CYP17A1CYP1A2TRPV1 | |
| SCHEMBL12871886 | 0.76 | MAPK14 (0.44) | HSD11B1ALDH1A1LMNAHTT | |
| SCHEMBL26387008 | 0.76 | LMNA (0.36) | OPRL1KCNH2CYP17A1CYP1A2HSD11B1 | |
| SCHEMBL12859503 | 0.76 | TRPV1 (0.39) | OPRL1KCNH2CYP17A1CYP1A2HSD11B1 | |
| SCHEMBL14996595 | 0.75 | OPRL1 (0.43) | OPRL1KCNH2CYP17A1CYP1A2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046152-A1 | Amide Compounds, Preparation Methods and Uses Thereof | SINOCHEM CORPORATION | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046152-A1 | Amide Compounds, Preparation Methods and Uses Thereof | ACHE, MGAM, PGLS | OPRL1 3194/4885KCNH2 1543/4885CYP17A1 3768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.