SCHEMBL12872379

SCHEMBL12872379

COC1C(CO)OC(C)C(NC(C)=O)C1O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.46
▸ ALDH1A1 P00352 1/20 0.44
▸ THRB P10828 1/20 0.44
▸ LGALS3 P17931 6/20 0.43
▸ LGALS8 O00214 2/20 0.43
▸ LGALS4 P56470 1/20 0.43
▸ LGALS1 P09382 1/20 0.42
▸ LGALS7; LGALS7B P47929 1/20 0.42
▸ LGALS9 O00182 1/20 0.41
▸ CD69 Q07108 1/20 0.40
▸ PYGB P11216 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23380129 1.00 MAPK1 (0.46) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL21122214 1.00 MAPK1 (0.46) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL26651047 1.00 MAPK1 (0.46) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL26651092 1.00 MAPK1 (0.46) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL12754153 1.00 MAPK1 (0.46) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL16311989 0.91 LGALS3 (0.53) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL21180426 0.91 LGALS3 (0.53) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL14865928 0.91 LGALS3 (0.53) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL15583488 0.91 LGALS3 (0.53) MAPK1ALDH1A1THRBLGALS3LGALS8
SCHEMBL16213792 0.91 LGALS3 (0.53) MAPK1ALDH1A1THRBLGALS3LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760991-B2 Multi-functional oxygenating microparticle loaded cell aggregates THE UNIVERSITY OF AKRON (US) 2023-09-19 — — US disclosed
US-20210147825-A1 MULTI-FUNCTIONAL OXYGENATING MICROPARTICLE LOADED CELL AGGREGATES THE UNIVERSITY OF AKRON 2021-05-20 — — US disclosed
US-10335490-B2 Fluorinated polymerizable hydrogels for wound dressings and methods of making same THE UNIVERSITY OF AKRON 2019-07-02 — — US disclosed
US-8563702-B2 Composite fibre of alginate and chitosan THE UNIVERSITY OF BOLTON EDUCATION CORPORATION (GB) 2013-10-22 — — US disclosed
US-7883615-B2 Selectively electrodepositing chitosan in spatially localized regions by contacting a conductive support of a substrate with an aqueous solution of a insoluble chitosan to form the polysaccharide hydrogel; coupling with biological cells and biomaterials UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2011-02-08 — — US disclosed
US-20090169639-A1 PARTICLES FOR INJECTION AND PROCESSES FOR FORMING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-07-02 — — US disclosed
US-20090169639-A1 PARTICLES FOR INJECTION AND PROCESSES FOR FORMING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2009-07-02 — — US disclosed
US-20090099353-A1 COMPOSITE FIBRE OF ALGINATE AND CHITOSAN THE UNIVERSITY OF BOLTON EDUCATION CORPORATION (GB) 2009-04-16 — — US disclosed
US-20090099353-A1 COMPOSITE FIBRE OF ALGINATE AND CHITOSAN THE UNIVERSITY OF BOLTON EDUCATION CORPORATION (GB) 2009-04-16 — — US disclosed
US-20070068824-A1 Controlled electrochemical deposition of polysaccharide films and hydrogels, and materials formed therefrom UNIVERSITY OF MARYLAND COLLEGE PARK 2007-03-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090169639-A1 PARTICLES FOR INJECTION AND PROCESSES FOR FORMING THE SAME CD44, CD47, ITGB5 MAPK1 3534/4885ALDH1A1 1940/4885THRB 3741/4885
US-20090099353-A1 COMPOSITE FIBRE OF ALGINATE AND CHITOSAN ALG1, CROCC, COL2A1 MAPK1 3358/4885ALDH1A1 2146/4885THRB 4519/4885
US-10335490-B2 Fluorinated polymerizable hydrogels for wound dressings and methods of making same FLNB, FLNA, QSOX1 MAPK1 1164/4885ALDH1A1 2358/4885THRB 4586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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