Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 12/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287482 | 0.86 | MEN1 (0.59) | TRPM8TAS2R14MEN1POLBKMT2A | |
| SCHEMBL1287387 | 0.85 | TAS2R14 (0.57) | TAS2R14MEN1POLBKMT2A | |
| SCHEMBL1287330 | 0.83 | MEN1 (0.64) | TAS2R14MEN1POLBKMT2A | |
| SCHEMBL1287485 | 0.73 | MEN1 (0.57) | TRPM8TAS2R14MEN1POLBKMT2A | |
| SCHEMBL1287322 | 0.72 | MEN1 (0.65) | TRPM8TAS2R14MEN1POLBKMT2A | |
| SCHEMBL1287293 | 0.71 | MEN1 (0.60) | TAS2R14MEN1POLBKMT2A | |
| SCHEMBL1287314 | 0.71 | MEN1 (0.77) | TAS2R14MEN1POLBKMT2A | |
| SCHEMBL1287531 | 0.71 | MEN1 (0.50) | TAS2R14MEN1POLBKMT2A | |
| SCHEMBL1287407 | 0.69 | TAS2R14 (0.81) | TAS2R14MEN1POLBKMT2A | |
| SCHEMBL1287426 | 0.68 | MEN1 (0.65) | TAS2R14MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |